Aspirin and dipyridamole and Vardenafil interaction

Aspirin and dipyridamole and Vardenafil: the Vardenafil prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Vardenafil (Vardenafil Hydrochloride) label · effective 2026-08-27

Moderate

There is no clinical evidence of any additive prolongation of the bleeding time when vardenafil is administered with aspirin.

Warnings and precautionsnames Aspirin and dipyridamoleView label on DailyMed
Moderate

Aspirin: Vardenafil hydrochloride tablets (10 mg and 20 mg) did not potentiate the increase in bleeding time caused by aspirin (two 81 mg tablets).

Drug interactionsnames Aspirin and dipyridamoleView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.