Butorphanol and Lisinopril and hydrochlorothiazide interaction
Butorphanol and Lisinopril and hydrochlorothiazide: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Lisinopril and hydrochlorothiazide (Zestoretic) label · effective 2025-03-31
Alcohol, barbiturates, or narcotics - potentiation of orthostatic hypotension may occur.
From the Butorphanol (Butorphanol Tartrate) label · effective 2026-01-02
In such cases, butorphanol should be discontinued and the hypertension treated with antihypertensive drugs.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.