Diltiazem and Ketamine interaction

Diltiazem and Ketamine: the Diltiazem prescribing label mentions this combination without an instruction to avoid it or change the dose.

Minor

Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.

What the FDA labels say

From the Diltiazem (DILTIAZEM HYDROCHLORIDE in SODIUM CHLORIDE) label · effective 2025-04-15

Minor

Anesthetics Depressed cardiac contractility, conductivity, and automaticity as well as the vascular dilation.

Drug interactionsby drug classView label on DailyMed
Minor

Anesthetics: Further depression of cardiac contractility, conductivity, and automaticity as well as vascular dilation.

Drug interactionsby drug classView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.