Dulaglutide and Losartan and hydrochlorothiazide interaction
Dulaglutide and Losartan and hydrochlorothiazide: the Losartan and hydrochlorothiazide prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Losartan and hydrochlorothiazide (HYZAAR) label · effective 2025-11-26
Antidiabetic drugs: dosage adjustment of antidiabetic may be required.
The Use of Hydrochlorothiazide with Other Drugs When administered concurrently, the following drugs may interact with thiazide diuretics [see Clinical Pharmacology (12.3) ]: Antidiabetic drugs (oral agents and insulin) — dosage adjustment of the antidiabetic drug may be required.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.