Dutasteride and Tamsulosin interaction

Dutasteride and Tamsulosin: the Dutasteride prescribing label mentions this combination without an instruction to avoid it or change the dose.

Minor

Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.

What the FDA labels say

From the Dutasteride label · effective 2026-01-13

Minor

Coadministration of dutasteride and tamsulosin resulted in similar changes to serum PSA as dutasteride monotherapy.

Warnings and precautionsnames TamsulosinView label on DailyMed
Minor

The effect of administration of tamsulosin or terazosin on dutasteride pharmacokinetic parameters has not been evaluated.

Drug interactionsnames TamsulosinView label on DailyMed
No interaction

Alpha-adrenergic Antagonists The administration of dutasteride capsules in combination with tamsulosin or terazosin has no effect on the steady-state pharmacokinetics of either alpha-adrenergic antagonist.

Drug interactionsby drug classView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.