Eslicarbazepine and Levothyroxine interaction

Eslicarbazepine and Levothyroxine: the Eslicarbazepine prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Eslicarbazepine (Aptiom) label · effective 2023-11-10

Moderate

Abnormal Thyroid Function Tests Dose-dependent decreases in serum T3 and T4 (free and total) values have been observed in patients taking APTIOM.

Warnings and precautionsby drug classView label on DailyMed
Minor

These changes were not associated with other abnormal thyroid function tests suggesting hypothyroidism.

Warnings and precautionsby drug classView label on DailyMed
Minor

Abnormal thyroid function tests should be clinically evaluated.

Warnings and precautionsby drug classView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.