Fexofenadine and Lisinopril and hydrochlorothiazide interaction

Fexofenadine and Lisinopril and hydrochlorothiazide: the Lisinopril and hydrochlorothiazide prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Lisinopril and hydrochlorothiazide (Zestoretic) label · effective 2025-03-31

Moderate

Even in those instances where swelling of only the tongue is involved, without respiratory distress, patients may require prolonged observation since treatment with antihistamines and corticosteroids may not be sufficient.

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Minor

Symptoms have not been relieved by antihistamines in these situations.

Warningsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.