Levomilnacipran and Naltrexone and bupropion interaction

Levomilnacipran and Naltrexone and bupropion: the Levomilnacipran prescribing label mentions this combination without an instruction to avoid it or change the dose.

Minor

Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.

What the FDA labels say

From the Levomilnacipran (Fetzima) label · effective 2024-04-30

Minor

Activation of mania/hypomania has also been reported in a small proportion of patients with mood disorders who were treated with other antidepressants.

Warnings and precautionsby drug classView label on DailyMed
Minor

Examples: other SNRIs, SSRIs, triptans, tricyclic antidepressants, opioids, lithium, buspirone, amphetamines, tryptophan, and St.

Drug interactionsby drug classView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.