Penicillin G and Valsartan and hydrochlorothiazide interaction
Penicillin G and Valsartan and hydrochlorothiazide: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Valsartan and hydrochlorothiazide (Diovan HCT) label · effective 2026-02-13
Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy.
From the Penicillin G (PENICILLIN G POTASSIUM) label · effective 2026-07-24
These drugs include: aspirin, phenylbutazone, sulfonamides, indomethacin, thiazide diuretics, furosemide and ethacrynic acid.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.