Aminocaproic acid interactions

Aminocaproic acid (Amicar), an antifibrinolytic has 5 documented interactions across the FDA labels and fact sheets we index: 4 major, 0 moderate, 1 minor, and 0 where a label reports no significant interaction. Each entry below quotes the sentence behind it. This drug page is a starting point, not a verdict for your situation.

Interactions from the label

Major interactions (4)

  • EnoxaparinanticoagulantMajor

    Aminocaproic acid must not be used in the presence of DIC without concomitant heparin. (Aminocaproic acid label, Contraindications)

  • HeparinanticoagulantMajor

    Aminocaproic acid must not be used in the presence of DIC without concomitant heparin. (Aminocaproic acid label, Contraindications)

  • • Protamine paracoagulation test is positive in DIC; a precipitate forms when protamine sulfate is dropped into citrated plasma. (Aminocaproic acid label, Contraindications)

  • TretinoinretinoidMajor

    Avoid concomitant use of tretinoin capsules and anti-fibrinolytic agents, such as tranexamic acid, aminocaproic acid or aprotinin [see Drug Interactions ( 7.4 )] . (Tretinoin label, Warnings and precautions)

Minor mentions (1)

  • ApixabananticoagulantMinor

    There is no experience with antifibrinolytic agents (tranexamic acid, aminocaproic acid) in individuals receiving apixaban. (Apixaban label, Warnings and precautions)

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Not medical advice. Severity reflects the label's wording, not your circumstances. A "major" flag can be routine under supervision and a "minor" one can matter at high doses. Ask a pharmacist.