Interaction Checker

Anastrozole interactions

Anastrozole (Arimidex), an aromatase inhibitor has 15 documented interactions across the FDA labels and fact sheets we index: 7 major, 0 moderate, 0 minor, and 8 where a label reports no significant interaction. Each entry below quotes the sentence behind it. This drug page is a starting point, not a verdict for your situation.

Major interactions (7)

  • Conjugated estrogensestrogenMajor

    Estrogen Estrogen-containing therapies should not be used with ARIMIDEX as they may diminish its pharmacological action. (Anastrozole label, Drug interactions)

  • Drospirenone and ethinyl estradioloral contraceptiveMajor

    Estrogen Estrogen-containing therapies should not be used with ARIMIDEX as they may diminish its pharmacological action. (Anastrozole label, Drug interactions)

  • EstradiolestrogenMajor

    Estrogen Estrogen-containing therapies should not be used with ARIMIDEX as they may diminish its pharmacological action. (Anastrozole label, Drug interactions)

  • Levonorgestrel and ethinyl estradioloral contraceptiveMajor

    Estrogen Estrogen-containing therapies should not be used with ARIMIDEX as they may diminish its pharmacological action. (Anastrozole label, Drug interactions)

  • Norethindrone and ethinyl estradioloral contraceptiveMajor

    Estrogen Estrogen-containing therapies should not be used with ARIMIDEX as they may diminish its pharmacological action. (Anastrozole label, Drug interactions)

  • Norgestimate and ethinyl estradioloral contraceptiveMajor

    Estrogen Estrogen-containing therapies should not be used with ARIMIDEX as they may diminish its pharmacological action. (Anastrozole label, Drug interactions)

  • Tamoxifenselective estrogen receptor modulatorMajor

    • Tamoxifen: Do not use in combination with ARIMIDEX. (Anastrozole label, Drug interactions)

No significant interaction reported (8)

  • ApixabananticoagulantNo interaction

    Warfarin In a study conducted in 16 male volunteers, anastrozole did not alter the exposure (as measured by C max and AUC) and anticoagulant activity (as measured by prothrombin time, activated partial thromboplastin time, and thrombin time) of both R- and S-warfarin. (Anastrozole label, Drug interactions)

  • DabigatrananticoagulantNo interaction

    Warfarin In a study conducted in 16 male volunteers, anastrozole did not alter the exposure (as measured by C max and AUC) and anticoagulant activity (as measured by prothrombin time, activated partial thromboplastin time, and thrombin time) of both R- and S-warfarin. (Anastrozole label, Drug interactions)

  • EdoxabananticoagulantNo interaction

    Warfarin In a study conducted in 16 male volunteers, anastrozole did not alter the exposure (as measured by C max and AUC) and anticoagulant activity (as measured by prothrombin time, activated partial thromboplastin time, and thrombin time) of both R- and S-warfarin. (Anastrozole label, Drug interactions)

  • EnoxaparinanticoagulantNo interaction

    Warfarin In a study conducted in 16 male volunteers, anastrozole did not alter the exposure (as measured by C max and AUC) and anticoagulant activity (as measured by prothrombin time, activated partial thromboplastin time, and thrombin time) of both R- and S-warfarin. (Anastrozole label, Drug interactions)

  • FondaparinuxanticoagulantNo interaction

    Warfarin In a study conducted in 16 male volunteers, anastrozole did not alter the exposure (as measured by C max and AUC) and anticoagulant activity (as measured by prothrombin time, activated partial thromboplastin time, and thrombin time) of both R- and S-warfarin. (Anastrozole label, Drug interactions)

  • HeparinanticoagulantNo interaction

    Warfarin In a study conducted in 16 male volunteers, anastrozole did not alter the exposure (as measured by C max and AUC) and anticoagulant activity (as measured by prothrombin time, activated partial thromboplastin time, and thrombin time) of both R- and S-warfarin. (Anastrozole label, Drug interactions)

  • RivaroxabananticoagulantNo interaction

    Warfarin In a study conducted in 16 male volunteers, anastrozole did not alter the exposure (as measured by C max and AUC) and anticoagulant activity (as measured by prothrombin time, activated partial thromboplastin time, and thrombin time) of both R- and S-warfarin. (Anastrozole label, Drug interactions)

  • WarfarinanticoagulantNo interaction

    Warfarin In a study conducted in 16 male volunteers, anastrozole did not alter the exposure (as measured by C max and AUC) and anticoagulant activity (as measured by prothrombin time, activated partial thromboplastin time, and thrombin time) of both R- and S-warfarin. (Anastrozole label, Drug interactions)

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Not medical advice. Severity reflects the label's wording, not your circumstances. A "major" flag can be routine under supervision and a "minor" one can matter at high doses. Ask a pharmacist.