Carmustine interactions

Carmustine (BiCNU, Gliadel) has 5 documented interactions across the FDA labels and fact sheets we index: 0 major, 4 moderate, 1 minor, and 0 where a label reports no significant interaction. Each entry below quotes the sentence behind it. This drug page is a starting point, not a verdict for your situation.

Interactions from the label

Moderate interactions (4)

  • CimetidineH2 blockerModerate

    Greater myelotoxicity (e.g., leukopenia and neutropenia) has been reported when carmustine was combined with cimetidine [see Drug Interactions (7) ] . (Carmustine label, Warnings and precautions)

  • PhenobarbitalbarbiturateModerate

    Consider alternative drugs to phenobarbital. (Carmustine label, Drug interactions)

  • Consider alternative drugs to phenobarbital. (Carmustine label, Drug interactions)

  • PhenytoinanticonvulsantModerate

    Phenytoin: Carmustine for Injection may reduce the efficacy of phenytoin. (Carmustine label, Drug interactions)

Minor mentions (1)

  • OndansetronQT-prolonging drugMinor

    Chemotherapy In humans, carmustine, etoposide, and cisplatin do not affect the pharmacokinetics of ondansetron. (Ondansetron label, Drug interactions)

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Not medical advice. Severity reflects the label's wording, not your circumstances. A "major" flag can be routine under supervision and a "minor" one can matter at high doses. Ask a pharmacist.