Cefoxitin interactions

Cefoxitin (Mefoxin), a cephalosporin has 63 documented interactions across the FDA labels and fact sheets we index: 27 major, 35 moderate, 1 minor, and 0 where a label reports no significant interaction. Each entry below quotes the sentence behind it. This drug page is a starting point, not a verdict for your situation.

Interactions from the label

Major interactions (27)

  • Amoxicillinpenicillin antibioticMajor

    Hypersensitivity to cefoxitin or other beta-lactam antibacterial drugs. (Cefoxitin label, Contraindications)

  • Amoxicillin and clavulanatepenicillin antibioticMajor

    Hypersensitivity to cefoxitin or other beta-lactam antibacterial drugs. (Cefoxitin label, Contraindications)

  • Ampicillinpenicillin antibioticMajor

    Hypersensitivity to cefoxitin or other beta-lactam antibacterial drugs. (Cefoxitin label, Contraindications)

  • Ampicillin and sulbactampenicillin antibioticMajor

    Hypersensitivity to cefoxitin or other beta-lactam antibacterial drugs. (Cefoxitin label, Contraindications)

  • CefaclorcephalosporinMajor

    Hypersensitivity to cefoxitin or other beta-lactam antibacterial drugs. (Cefoxitin label, Contraindications)

  • CefadroxilcephalosporinMajor

    Hypersensitivity to cefoxitin or other beta-lactam antibacterial drugs. (Cefoxitin label, Contraindications)

  • CefazolincephalosporinMajor

    Hypersensitivity to cefoxitin or other beta-lactam antibacterial drugs. (Cefoxitin label, Contraindications)

  • CefdinircephalosporinMajor

    Hypersensitivity to cefoxitin or other beta-lactam antibacterial drugs. (Cefoxitin label, Contraindications)

  • CefepimecephalosporinMajor

    Hypersensitivity to cefoxitin or other beta-lactam antibacterial drugs. (Cefoxitin label, Contraindications)

  • CefiximecephalosporinMajor

    Hypersensitivity to cefoxitin or other beta-lactam antibacterial drugs. (Cefoxitin label, Contraindications)

  • CefotaximecephalosporinMajor

    Hypersensitivity to cefoxitin or other beta-lactam antibacterial drugs. (Cefoxitin label, Contraindications)

  • CefotetancephalosporinMajor

    Hypersensitivity to cefoxitin or other beta-lactam antibacterial drugs. (Cefoxitin label, Contraindications)

  • CefpodoximecephalosporinMajor

    Hypersensitivity to cefoxitin or other beta-lactam antibacterial drugs. (Cefoxitin label, Contraindications)

  • CefprozilcephalosporinMajor

    Hypersensitivity to cefoxitin or other beta-lactam antibacterial drugs. (Cefoxitin label, Contraindications)

  • CeftarolinecephalosporinMajor

    Hypersensitivity to cefoxitin or other beta-lactam antibacterial drugs. (Cefoxitin label, Contraindications)

  • CeftazidimecephalosporinMajor

    Hypersensitivity to cefoxitin or other beta-lactam antibacterial drugs. (Cefoxitin label, Contraindications)

  • CeftriaxonecephalosporinMajor

    Hypersensitivity to cefoxitin or other beta-lactam antibacterial drugs. (Cefoxitin label, Contraindications)

  • CefuroximecephalosporinMajor

    Hypersensitivity to cefoxitin or other beta-lactam antibacterial drugs. (Cefoxitin label, Contraindications)

  • CephalexincephalosporinMajor

    Hypersensitivity to cefoxitin or other beta-lactam antibacterial drugs. (Cefoxitin label, Contraindications)

  • Dicloxacillinpenicillin antibioticMajor

    Hypersensitivity to cefoxitin or other beta-lactam antibacterial drugs. (Cefoxitin label, Contraindications)

  • ErtapenemantibioticMajor

    INVANZ is contraindicated in patients with known hypersensitivity to any component of this product or to other drugs in the same class or in patients who have demonstrated anaphylactic reactions to beta-lactams. (Ertapenem label, Contraindications)

  • Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (Imipenem and cilastatin label, Warnings and precautions)

  • Nafcillinpenicillin antibioticMajor

    Hypersensitivity to cefoxitin or other beta-lactam antibacterial drugs. (Cefoxitin label, Contraindications)

  • Oxacillinpenicillin antibioticMajor

    Hypersensitivity to cefoxitin or other beta-lactam antibacterial drugs. (Cefoxitin label, Contraindications)

  • Penicillin Gpenicillin antibioticMajor

    Hypersensitivity to cefoxitin or other beta-lactam antibacterial drugs. (Cefoxitin label, Contraindications)

  • Penicillin Vpenicillin antibioticMajor

    Hypersensitivity to cefoxitin or other beta-lactam antibacterial drugs. (Cefoxitin label, Contraindications)

  • Piperacillin and tazobactampenicillin antibioticMajor

    Hypersensitivity to cefoxitin or other beta-lactam antibacterial drugs. (Cefoxitin label, Contraindications)

Moderate interactions (35)

  • AmikacinaminoglycosideModerate

    Aminoglycosides: Increased potential of nephrotoxicity. (Cefoxitin label, Drug interactions)

  • Azelastine and fluticasoneantihistamineModerate

    High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (Cefoxitin label, Warnings and precautions)

  • AztreonamantibioticModerate

    Use caution when CAYSTON is administered to patients with a known allergic reaction to beta-lactams. (Aztreonam label, Warnings and precautions)

  • BeclomethasonecorticosteroidModerate

    High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (Cefoxitin label, Warnings and precautions)

  • BetamethasonecorticosteroidModerate

    High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (Cefoxitin label, Warnings and precautions)

  • BudesonidecorticosteroidModerate

    High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (Cefoxitin label, Warnings and precautions)

  • Budesonide and formoterolcorticosteroidModerate

    High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (Cefoxitin label, Warnings and precautions)

  • CiclesonidecorticosteroidModerate

    High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (Cefoxitin label, Warnings and precautions)

  • ClobetasolcorticosteroidModerate

    High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (Cefoxitin label, Warnings and precautions)

  • DeflazacortcorticosteroidModerate

    High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (Cefoxitin label, Warnings and precautions)

  • DesonidecorticosteroidModerate

    High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (Cefoxitin label, Warnings and precautions)

  • DexamethasonecorticosteroidModerate

    High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (Cefoxitin label, Warnings and precautions)

  • Ethacrynic acidloop diureticModerate

    Ethacrynic acid may increase the ototoxic potential of other drugs such as aminoglycoside and some cephalosporin antibiotics. (Ethacrynic acid label, Drug interactions)

  • FludrocortisonecorticosteroidModerate

    High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (Cefoxitin label, Warnings and precautions)

  • FlunisolidecorticosteroidModerate

    High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (Cefoxitin label, Warnings and precautions)

  • FluocinonidecorticosteroidModerate

    High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (Cefoxitin label, Warnings and precautions)

  • FluticasonecorticosteroidModerate

    High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (Cefoxitin label, Warnings and precautions)

  • Fluticasone and salmeterolcorticosteroidModerate

    High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (Cefoxitin label, Warnings and precautions)

  • Furosemideloop diureticModerate

    Cephalosporin Furosemide can increase the risk of cephalosporin-induced nephrotoxicity even in the setting of minor or transient renal impairment. (Furosemide label, Drug interactions)

  • GentamicinaminoglycosideModerate

    Aminoglycosides: Increased potential of nephrotoxicity. (Cefoxitin label, Drug interactions)

  • HalobetasolcorticosteroidModerate

    High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (Cefoxitin label, Warnings and precautions)

  • HydrocortisonecorticosteroidModerate

    High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (Cefoxitin label, Warnings and precautions)

  • MethylprednisolonecorticosteroidModerate

    High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (Cefoxitin label, Warnings and precautions)

  • MometasonecorticosteroidModerate

    High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (Cefoxitin label, Warnings and precautions)

  • MycophenolateimmunosuppressantModerate

    Examples Cyclosporine A, trimethoprim/sulfamethoxazole, bile acid sequestrants (cholestyramine), rifampin as well as aminoglycoside, cephalosporin, fluoroquinolone and penicillin classes of antimicrobials Drugs Modulating Glucuronidation Clinical Impact Concomitant use with drugs inducing glucuronidation decreases MPA systemic exposure, potentially reducing mycophenolate… (Mycophenolate label, Drug interactions)

  • NeomycinaminoglycosideModerate

    Aminoglycosides: Increased potential of nephrotoxicity. (Cefoxitin label, Drug interactions)

  • Olopatadine and mometasoneantihistamineModerate

    High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (Cefoxitin label, Warnings and precautions)

  • PlazomicinaminoglycosideModerate

    Aminoglycosides: Increased potential of nephrotoxicity. (Cefoxitin label, Drug interactions)

  • PrednisolonecorticosteroidModerate

    High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (Cefoxitin label, Warnings and precautions)

  • PrednisonecorticosteroidModerate

    High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (Cefoxitin label, Warnings and precautions)

  • ProbenecidModerate

    Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (Probenecid label, Drug interactions)

  • DRUG INTERACTIONS When probenecid is used to elevate plasma concentrations of penicillin, or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug. (Probenecid and colchicine label, Drug interactions)

  • ProtamineModerate

    Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (Protamine label, Precautions)

  • TobramycinaminoglycosideModerate

    Aminoglycosides: Increased potential of nephrotoxicity. (Cefoxitin label, Drug interactions)

  • TriamcinolonecorticosteroidModerate

    High concentrations of cefoxitin in the urine may interfere with measurement of urinary 17-hydroxy-corticosteroids by the Porter-Silber reaction, and produce false increases of modest degree in the levels reported. (Cefoxitin label, Warnings and precautions)

Minor mentions (1)

  • MeropenemantibioticMinor

    Before initiating therapy with Meropenem for injection, it is important to inquire about previous hypersensitivity reactions to penicillins, cephalosporins, other β-lactams, and other allergens. (Meropenem label, Warnings and precautions)

Check Cefoxitin against everything you take. Add your full list; every pair is checked at once.

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Not medical advice. Severity reflects the label's wording, not your circumstances. A "major" flag can be routine under supervision and a "minor" one can matter at high doses. Ask a pharmacist.