Interaction Checker

Clofarabine interactions

Clofarabine (Clolar), an antimetabolite has 56 documented interactions across the FDA labels and fact sheets we index: 0 major, 33 moderate, 23 minor, and 0 where a label reports no significant interaction. Each entry below quotes the sentence behind it. This drug page is a starting point, not a verdict for your situation.

Interactions from the label

Moderate interactions (33)

  • Acetazolamidecarbonic anhydrase inhibitorModerate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Amiloridepotassium-sparing diureticModerate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Atenolol and chlorthalidonebeta blockerModerate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Benazepril and hydrochlorothiazideACE inhibitorModerate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Bisoprolol and hydrochlorothiazidebeta blockerModerate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Bumetanideloop diureticModerate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Candesartan and hydrochlorothiazideangiotensin II receptor blocker (ARB)Moderate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Chlorothiazidethiazide diureticModerate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Chlorthalidonethiazide diureticModerate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • CyclophosphamideimmunosuppressantModerate

    Venous Occlusive Disease of the Liver Patients who have previously received a hematopoietic stem cell transplant (HSCT) are at higher risk for veno-occlusive disease (VOD) of the liver following treatment with clofarabine (40 mg/m 2 ) when used in combination with etoposide (100 mg/m 2 ) and cyclophosphamide (440 mg/m 2 ). (Clofarabine label, Warnings and precautions)

  • Enalapril and hydrochlorothiazideACE inhibitorModerate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Eplerenonealdosterone antagonistModerate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Ethacrynic acidloop diureticModerate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • EtoposideModerate

    Venous Occlusive Disease of the Liver Patients who have previously received a hematopoietic stem cell transplant (HSCT) are at higher risk for veno-occlusive disease (VOD) of the liver following treatment with clofarabine (40 mg/m 2 ) when used in combination with etoposide (100 mg/m 2 ) and cyclophosphamide (440 mg/m 2 ). (Clofarabine label, Warnings and precautions)

  • Fosinopril and hydrochlorothiazideACE inhibitorModerate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Furosemideloop diureticModerate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Hydrochlorothiazidethiazide diureticModerate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Indapamidethiazide diureticModerate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Irbesartan and hydrochlorothiazideangiotensin II receptor blocker (ARB)Moderate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Lisinopril and hydrochlorothiazideACE inhibitorModerate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Losartan and hydrochlorothiazideangiotensin II receptor blocker (ARB)Moderate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Metolazonethiazide diureticModerate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Metoprolol and hydrochlorothiazidebeta blockerModerate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Olmesartan and hydrochlorothiazideangiotensin II receptor blocker (ARB)Moderate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Olmesartan, amlodipine, and hydrochlorothiazideangiotensin II receptor blocker (ARB)Moderate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Quinapril and hydrochlorothiazideACE inhibitorModerate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Spironolactonealdosterone antagonistModerate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Spironolactone and hydrochlorothiazidealdosterone antagonistModerate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Telmisartan and hydrochlorothiazideangiotensin II receptor blocker (ARB)Moderate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Torsemideloop diureticModerate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Triamterenepotassium-sparing diureticModerate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Triamterene and hydrochlorothiazidepotassium-sparing diureticModerate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

  • Valsartan and hydrochlorothiazideangiotensin II receptor blocker (ARB)Moderate

    Consider use of diuretics and/or albumin. (Clofarabine label, Warnings and precautions)

Minor mentions (23)

  • Azelastine and fluticasoneantihistamineMinor

    The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (Clofarabine label, Warnings and precautions)

  • BeclomethasonecorticosteroidMinor

    The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (Clofarabine label, Warnings and precautions)

  • BetamethasonecorticosteroidMinor

    The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (Clofarabine label, Warnings and precautions)

  • BudesonidecorticosteroidMinor

    The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (Clofarabine label, Warnings and precautions)

  • Budesonide and formoterolcorticosteroidMinor

    The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (Clofarabine label, Warnings and precautions)

  • CiclesonidecorticosteroidMinor

    The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (Clofarabine label, Warnings and precautions)

  • ClobetasolcorticosteroidMinor

    The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (Clofarabine label, Warnings and precautions)

  • DeflazacortcorticosteroidMinor

    The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (Clofarabine label, Warnings and precautions)

  • DesonidecorticosteroidMinor

    The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (Clofarabine label, Warnings and precautions)

  • DexamethasonecorticosteroidMinor

    The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (Clofarabine label, Warnings and precautions)

  • FludrocortisonecorticosteroidMinor

    The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (Clofarabine label, Warnings and precautions)

  • FlunisolidecorticosteroidMinor

    The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (Clofarabine label, Warnings and precautions)

  • FluocinonidecorticosteroidMinor

    The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (Clofarabine label, Warnings and precautions)

  • FluticasonecorticosteroidMinor

    The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (Clofarabine label, Warnings and precautions)

  • Fluticasone and salmeterolcorticosteroidMinor

    The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (Clofarabine label, Warnings and precautions)

  • HalobetasolcorticosteroidMinor

    The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (Clofarabine label, Warnings and precautions)

  • HydrocortisonecorticosteroidMinor

    The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (Clofarabine label, Warnings and precautions)

  • MethylprednisolonecorticosteroidMinor

    The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (Clofarabine label, Warnings and precautions)

  • MometasonecorticosteroidMinor

    The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (Clofarabine label, Warnings and precautions)

  • Olopatadine and mometasoneantihistamineMinor

    The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (Clofarabine label, Warnings and precautions)

  • PrednisolonecorticosteroidMinor

    The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (Clofarabine label, Warnings and precautions)

  • PrednisonecorticosteroidMinor

    The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (Clofarabine label, Warnings and precautions)

  • TriamcinolonecorticosteroidMinor

    The use of prophylactic steroids (e.g., 100 mg/m 2 hydrocortisone on Days 1 through 3) may be of benefit in preventing signs or symptoms of SIRS or capillary leak syndrome. (Clofarabine label, Warnings and precautions)

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Not medical advice. Severity reflects the label's wording, not your circumstances. A "major" flag can be routine under supervision and a "minor" one can matter at high doses. Ask a pharmacist.