Etoposide interactions
Etoposide (Toposar, Etopophos, VePesid) has 6 documented interactions across the FDA labels and fact sheets we index: 0 major, 3 moderate, 1 minor, and 2 where a label reports no significant interaction. Each entry below quotes the sentence behind it. This drug page is a starting point, not a verdict for your situation.
Interactions from the label
Moderate interactions (3)
Venous Occlusive Disease of the Liver Patients who have previously received a hematopoietic stem cell transplant (HSCT) are at higher risk for veno-occlusive disease (VOD) of the liver following treatment with clofarabine (40 mg/m 2 ) when used in combination with etoposide (100 mg/m 2 ) and cyclophosphamide (440 mg/m 2 ). (Clofarabine label, Warnings and precautions)
Cyclosporine may reduce the clearance of digoxin, colchicine, prednisolone, HMG-CoA reductase inhibitors (statins), aliskiren, bosentan, dabigatran, repaglinide, NSAIDs, sirolimus, etoposide, and other drugs. (Cyclosporine label, Drug interactions)
Warfarin: Co-administration of ETOPOPHOS with warfarin can result in elevated international normalized ratio (INR). (Etoposide label, Drug interactions)
Minor mentions (1)
Chemotherapy In humans, carmustine, etoposide, and cisplatin do not affect the pharmacokinetics of ondansetron. (Ondansetron label, Drug interactions)
No significant interaction reported (2)
Etoposide, vinorelbine, paclitaxel, and docetaxel No dosage adjustment needed. (Aprepitant label, Drug interactions)
Etoposide, vinorelbine, paclitaxel, and docetaxel No dosage adjustment needed. (Fosaprepitant label, Drug interactions)
Check Etoposide against everything you take. Add your full list; every pair is checked at once.
Open in the checkerNot medical advice. Severity reflects the label's wording, not your circumstances. A "major" flag can be routine under supervision and a "minor" one can matter at high doses. Ask a pharmacist.