Interaction Checker

Gemcitabine interactions

Gemcitabine (Gemzar, Infugem), an antimetabolite has 3 documented interactions across the FDA labels and fact sheets we index: 2 major, 0 moderate, 1 minor, and 0 where a label reports no significant interaction. Each entry below quotes the sentence behind it. This drug page is a starting point, not a verdict for your situation.

Interactions from the label

Major interactions (2)

  • PaclitaxelMajor

    Pneumonitis Pneumonitis, including some cases that were fatal, occurred in 4% of patients receiving protein bound paclitaxel in combination with gemcitabine. (Paclitaxel label, Warnings and precautions)

  • SorafenibMajor

    NEXAVAR in combination with gemcitabine/cisplatin is not recommended in patients with squamous cell lung cancer. (Sorafenib label, Warnings and precautions)

Minor mentions (1)

  • ErlotinibMinor

    The incidence of renal impairment in the pancreatic cancer study was 1.4% in the erlotinib plus gemcitabine arm and 0.4% in the control arm. (Erlotinib label, Warnings and precautions)

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Not medical advice. Severity reflects the label's wording, not your circumstances. A "major" flag can be routine under supervision and a "minor" one can matter at high doses. Ask a pharmacist.