Interferon beta-1a interactions

Interferon beta-1a (Avonex, Rebif, Plegridy) has 6 documented interactions across the FDA labels and fact sheets we index: 0 major, 5 moderate, 1 minor, and 0 where a label reports no significant interaction. Each entry below quotes the sentence behind it. This drug page is a starting point, not a verdict for your situation.

Moderate interactions (5)

  • AlcoholAlcoholModerate

    The potential risk of AVONEX used in combination with known hepatotoxic drugs or other products (e.g., alcohol) should be considered prior to starting AVONEX, or before starting hepatotoxic drugs. (Interferon beta-1a label, Warnings and precautions)

  • Levothyroxinethyroid hormoneModerate

    Thyroid function should be monitored periodically. (Interferon beta-1a label, Warnings and precautions)

  • Liothyroninethyroid hormoneModerate

    Thyroid function should be monitored periodically. (Interferon beta-1a label, Warnings and precautions)

  • Methimazoleantithyroid drugModerate

    Thyroid function should be monitored periodically. (Interferon beta-1a label, Warnings and precautions)

  • Propylthiouracilantithyroid drugModerate

    Thyroid function should be monitored periodically. (Interferon beta-1a label, Warnings and precautions)

Minor mentions (1)

  • OcrelizumabimmunosuppressantMinor

    A higher proportion of adult patients treated with OCREVUS experienced infections compared to patients taking REBIF or placebo. (Ocrelizumab label, Warnings and precautions)

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Not medical advice. Severity reflects the label's wording, not your circumstances. A "major" flag can be routine under supervision and a "minor" one can matter at high doses. Ask a pharmacist.