Interaction Checker

Mepolizumab interactions

Mepolizumab (Nucala) has 23 documented interactions across the FDA labels and fact sheets we index: 0 major, 23 moderate, 0 minor, and 0 where a label reports no significant interaction. Each entry below quotes the sentence behind it. This drug page is a starting point, not a verdict for your situation.

Interactions from the label

Moderate interactions (23)

  • Azelastine and fluticasoneantihistamineModerate

    Decrease corticosteroids gradually, if appropriate. (Mepolizumab label, Warnings and precautions)

  • BeclomethasonecorticosteroidModerate

    Decrease corticosteroids gradually, if appropriate. (Mepolizumab label, Warnings and precautions)

  • BetamethasonecorticosteroidModerate

    Decrease corticosteroids gradually, if appropriate. (Mepolizumab label, Warnings and precautions)

  • BudesonidecorticosteroidModerate

    Decrease corticosteroids gradually, if appropriate. (Mepolizumab label, Warnings and precautions)

  • Budesonide and formoterolcorticosteroidModerate

    Decrease corticosteroids gradually, if appropriate. (Mepolizumab label, Warnings and precautions)

  • CiclesonidecorticosteroidModerate

    Decrease corticosteroids gradually, if appropriate. (Mepolizumab label, Warnings and precautions)

  • ClobetasolcorticosteroidModerate

    Decrease corticosteroids gradually, if appropriate. (Mepolizumab label, Warnings and precautions)

  • DeflazacortcorticosteroidModerate

    Decrease corticosteroids gradually, if appropriate. (Mepolizumab label, Warnings and precautions)

  • DesonidecorticosteroidModerate

    Decrease corticosteroids gradually, if appropriate. (Mepolizumab label, Warnings and precautions)

  • DexamethasonecorticosteroidModerate

    Decrease corticosteroids gradually, if appropriate. (Mepolizumab label, Warnings and precautions)

  • FludrocortisonecorticosteroidModerate

    Decrease corticosteroids gradually, if appropriate. (Mepolizumab label, Warnings and precautions)

  • FlunisolidecorticosteroidModerate

    Decrease corticosteroids gradually, if appropriate. (Mepolizumab label, Warnings and precautions)

  • FluocinonidecorticosteroidModerate

    Decrease corticosteroids gradually, if appropriate. (Mepolizumab label, Warnings and precautions)

  • FluticasonecorticosteroidModerate

    Decrease corticosteroids gradually, if appropriate. (Mepolizumab label, Warnings and precautions)

  • Fluticasone and salmeterolcorticosteroidModerate

    Decrease corticosteroids gradually, if appropriate. (Mepolizumab label, Warnings and precautions)

  • HalobetasolcorticosteroidModerate

    Decrease corticosteroids gradually, if appropriate. (Mepolizumab label, Warnings and precautions)

  • HydrocortisonecorticosteroidModerate

    Decrease corticosteroids gradually, if appropriate. (Mepolizumab label, Warnings and precautions)

  • MethylprednisolonecorticosteroidModerate

    Decrease corticosteroids gradually, if appropriate. (Mepolizumab label, Warnings and precautions)

  • MometasonecorticosteroidModerate

    Decrease corticosteroids gradually, if appropriate. (Mepolizumab label, Warnings and precautions)

  • Olopatadine and mometasoneantihistamineModerate

    Decrease corticosteroids gradually, if appropriate. (Mepolizumab label, Warnings and precautions)

  • PrednisolonecorticosteroidModerate

    Decrease corticosteroids gradually, if appropriate. (Mepolizumab label, Warnings and precautions)

  • PrednisonecorticosteroidModerate

    Decrease corticosteroids gradually, if appropriate. (Mepolizumab label, Warnings and precautions)

  • TriamcinolonecorticosteroidModerate

    Decrease corticosteroids gradually, if appropriate. (Mepolizumab label, Warnings and precautions)

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Not medical advice. Severity reflects the label's wording, not your circumstances. A "major" flag can be routine under supervision and a "minor" one can matter at high doses. Ask a pharmacist.