Senna (sennosides) interactions
Senna (sennosides) (Senokot, Ex-Lax), a laxative has 9 documented interactions across the FDA labels and fact sheets we index: 1 major, 5 moderate, 3 minor, and 0 where a label reports no significant interaction. Each entry below quotes the sentence behind it. This drug page is a starting point, not a verdict for your situation.
Major interactions (1)
- RisedronatebisphosphonateMajor
Calcium supplements, antacids, magnesium-based supplements or laxatives, and iron preparations interfere with the absorption of Risedronate sodium delayed-release and should not be taken together. (Risedronate label, Drug interactions)
Moderate interactions (5)
- AmiodaroneantiarrhythmicModerate
Give special attention to electrolyte and acid-base balance in patients experiencing severe or prolonged diarrhea or in patients receiving concomitant diuretics and laxatives. (Amiodarone label, Warnings and precautions)
- ClozapineantipsychoticModerate
If constipation or gastrointestinal hypomotility are identified, monitor closely and treat promptly with appropriate laxatives, as necessary, to prevent severe complications. (Clozapine label, Warnings and precautions)
- GlimepiridesulfonylureaModerate
…leading to worsening glycemic control: danazol, glucagon, somatropin, protease inhibitors, atypical antipsychotic medications (e.g., olanzapine and clozapine), barbiturates, diazoxide, laxatives, rifampin, thiazides and other diuretics, corticosteroids, phenothiazines, thyroid hormones, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics (e.g.,… (Glimepiride label, Drug interactions)
- Nifedipinedihydropyridine calcium channel blockerModerate
…diverticulosis, and inflammatory bowel disease), hypomotility disorders (e.g., constipation, gastroesophageal reflux disease, ileus, obesity, hypothyroidism, and diabetes) and concomitant medications (e.g., H 2 -histamine blockers, opiates, nonsteroidal anti-inflammatory drugs, laxatives, anticholinergic agents, levothyroxine, and neuromuscular blocking agents). (Nifedipine label, Warnings)
- Triamterene and hydrochlorothiazidepotassium-sparing diureticModerate
Chronic or overuse of laxatives may reduce serum potassium levels by promoting excessive potassium loss from the intestinal tract; laxatives may interfere with the potassium-retaining effects of triamterene. (Triamterene and hydrochlorothiazide label, Drug interactions)
Minor mentions (3)
- Bictegravir, emtricitabine, and tenofovir alafenamideantiretroviralMinor
Oral medications or supplements containing polyvalent cations (e.g., Mg, Al, Ca, Fe): Calcium or iron supplements Cation-containing antacids or laxatives Sucralfate Buffered medications ↓ bictegravir Antacids containing Al/Mg : Take BIXLENVO at least 2 hours before or 6 hours after taking antacids containing Al/Mg. (Bictegravir, emtricitabine, and tenofovir alafenamide label, Drug interactions)
- DolutegravirantiretroviralMinor
TIVICAY or TIVICAY PD should be taken 2 hours before or 6 hours after taking cation-containing antacids or laxatives, sucralfate, oral supplements containing iron or calcium, or buffered medications. (Dolutegravir label, Drug interactions)
- MethadoneopioidMinor
Drugs capable of inducing electrolyte disturbances: Diuretics, laxatives, and, in rare cases, mineralocortocoid hormones. (Methadone label, Drug interactions)
Check Senna (sennosides) against everything you take. Add your full list; every pair is checked at once.
Open in the checkerNot medical advice. Severity reflects the label's wording, not your circumstances. A "major" flag can be routine under supervision and a "minor" one can matter at high doses. Ask a pharmacist.