Busulfan : interactions médicamenteuses

Busulfan (Myleran, Busulfex) présente 37 interactions documentées dans les notices FDA et les fiches d'information que nous indexons : 3 de niveau majeur, 4 de niveau modéré, 30 de niveau mineur et 0 cas où une notice ne signale aucune interaction significative. Chaque entrée ci-dessous cite la phrase sur laquelle elle repose. Cette page consacrée à un médicament est un point de départ, pas un verdict sur votre situation.

Interactions d'après la notice

Interactions majeures (3)

  • CyclophosphamideimmunosuppresseurMajeure

    Hepatic veno-occlusive disease, which may be life threatening, has been reported in patients receiving busulfan, usually in combination with cyclophosphamide or other chemotherapeutic agents prior to bone marrow transplantation. (notice Busulfan, Mises en garde)

  • MétronidazoleantibiotiqueMajeure

    Busulfan : Increased busulfan serum concentrations; avoid concomitant use, monitor for plasma concentrations and adjust the busulfan dose accordingly. (notice Métronidazole, Interactions médicamenteuses)

  • Do not administer bismuth subcitrate potassium, metronidazole and tetracycline hydrochloride concomitantly with busulfan unless the benefit outweighs the risk. (notice Sous-citrate de bismuth, métronidazole et tétracycline, Mises en garde et précautions)

Interactions modérées (4)

  • Déférasiroxsupplément de ferModérée

    Deferasirox increases exposure of busulfan. (notice Déférasirox, Interactions médicamenteuses)

  • IfosfamideModérée

    Hemorrhagic cystitis is dose‑dependent and the risk is increased with past or concomitant radiation of the bladder or busulfan treatment. (notice Ifosfamide, Mises en garde et précautions)

  • Itraconazoleantifongique azoléModérée

    The concomitant systemic administration of itraconazole to patients receiving high-dose MYLERAN may result in reduced busulfan clearance (see CLINICAL PHARMACOLOGY). (notice Busulfan, Interactions médicamenteuses)

  • ThiotépaModérée

    Hepatic Veno-Occlusive Disease Hepatic veno-occlusive disease may occur in patients who have received high-dose TEPADINA in conjunction with busulfan and cyclophosphamide [ see Adverse Reactions (6.1) ]. (notice Thiotépa, Mises en garde et précautions)

Mentions mineures (30)

  • Azélastine et fluticasoneantihistaminiqueMineure

    The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (notice Busulfan, Mises en garde)

  • BéclométasonecorticoïdeMineure

    The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (notice Busulfan, Mises en garde)

  • BétaméthasonecorticoïdeMineure

    The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (notice Busulfan, Mises en garde)

  • BudésonidecorticoïdeMineure

    The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (notice Busulfan, Mises en garde)

  • Budésonide et formotérolcorticoïdeMineure

    The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (notice Busulfan, Mises en garde)

  • CiclésonidecorticoïdeMineure

    The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (notice Busulfan, Mises en garde)

  • ClobétasolcorticoïdeMineure

    The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (notice Busulfan, Mises en garde)

  • DéflazacortcorticoïdeMineure

    The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (notice Busulfan, Mises en garde)

  • DésonidecorticoïdeMineure

    The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (notice Busulfan, Mises en garde)

  • DexaméthasonecorticoïdeMineure

    The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (notice Busulfan, Mises en garde)

  • FludrocortisonecorticoïdeMineure

    The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (notice Busulfan, Mises en garde)

  • FlunisolidecorticoïdeMineure

    The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (notice Busulfan, Mises en garde)

  • FluocinonidecorticoïdeMineure

    The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (notice Busulfan, Mises en garde)

  • FluticasonecorticoïdeMineure

    The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (notice Busulfan, Mises en garde)

  • Fluticasone et salmétérolcorticoïdeMineure

    The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (notice Busulfan, Mises en garde)

  • HalobétasolcorticoïdeMineure

    The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (notice Busulfan, Mises en garde)

  • HydrocortisonecorticoïdeMineure

    The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (notice Busulfan, Mises en garde)

  • Lévothyroxinehormone thyroïdienneMineure

    Cytologic abnormalities characterized by giant, hyperchromatic nuclei have been reported in lymph nodes, pancreas, thyroid, adrenal glands, liver, and bone marrow. (notice Busulfan, Mises en garde)

  • Lévothyroxine et liothyroninehormone thyroïdienneMineure

    Cytologic abnormalities characterized by giant, hyperchromatic nuclei have been reported in lymph nodes, pancreas, thyroid, adrenal glands, liver, and bone marrow. (notice Busulfan, Mises en garde)

  • Liothyroninehormone thyroïdienneMineure

    Cytologic abnormalities characterized by giant, hyperchromatic nuclei have been reported in lymph nodes, pancreas, thyroid, adrenal glands, liver, and bone marrow. (notice Busulfan, Mises en garde)

  • MercaptopurineantimétaboliteMineure

    During the pregnancy that resulted in the malformed infant, the mother received x-ray therapy early in the first trimester, mercaptopurine until the third month, then busulfan until delivery. (notice Busulfan, Mises en garde)

  • MéthylprednisolonecorticoïdeMineure

    The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (notice Busulfan, Mises en garde)

  • MométasonecorticoïdeMineure

    The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (notice Busulfan, Mises en garde)

  • Olopatadine et mométasoneantihistaminiqueMineure

    The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (notice Busulfan, Mises en garde)

  • PrednisolonecorticoïdeMineure

    The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (notice Busulfan, Mises en garde)

  • PrednisonecorticoïdeMineure

    The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (notice Busulfan, Mises en garde)

  • PropylthiouracileantithyroïdienMineure

    Cytologic abnormalities characterized by giant, hyperchromatic nuclei have been reported in lymph nodes, pancreas, thyroid, adrenal glands, liver, and bone marrow. (notice Busulfan, Mises en garde)

  • Tériparatidehormone thyroïdienneMineure

    Cytologic abnormalities characterized by giant, hyperchromatic nuclei have been reported in lymph nodes, pancreas, thyroid, adrenal glands, liver, and bone marrow. (notice Busulfan, Mises en garde)

  • ThiamazoleantithyroïdienMineure

    Cytologic abnormalities characterized by giant, hyperchromatic nuclei have been reported in lymph nodes, pancreas, thyroid, adrenal glands, liver, and bone marrow. (notice Busulfan, Mises en garde)

  • TriamcinolonecorticoïdeMineure

    The administration of corticosteroids has been suggested, but the results have not been impressive or uniformly successful. (notice Busulfan, Mises en garde)

Vérifiez Busulfan avec tout ce que vous prenez. Ajoutez votre liste complète ; toutes les paires sont vérifiées en une fois.

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Ceci n'est pas un avis médical. Le niveau de gravité reflète la formulation de la notice, pas votre situation. Une alerte « majeure » peut être courante sous surveillance et une alerte « mineure » peut compter à forte dose. Demandez conseil à un pharmacien.