Caspofungine : interactions médicamenteuses

Caspofungine (Cancidas), antifongique, présente 34 interactions documentées dans les notices FDA et les fiches d'information que nous indexons : 1 de niveau majeur, 33 de niveau modéré, 0 de niveau mineur et 0 cas où une notice ne signale aucune interaction significative. Chaque entrée ci-dessous cite la phrase sur laquelle elle repose. Cette page consacrée à un médicament est un point de départ, pas un verdict sur votre situation.

Interactions d'après la notice

Interactions majeures (1)

  • RifampicineantibiotiqueMajeure

    …of anticoagulant Warfarin Decrease exposure Antifungals Fluconazole Decrease AUC by 23% Itraconazole Prevention or Management: Not recommended 2 weeks before and during itraconazole treatment Decrease exposure Ketoconazole Decrease exposure Caspofungin Prevention or Management: Refer to the caspofungin prescribing information for caspofungin dose adjustment. (notice Rifampicine, Interactions médicamenteuses)

Interactions modérées (33)

  • Aprépitantinhibiteur du CYP3A4Modérée

    Inducers of Hepatic CYP Enzymes Rifampin : Rifampin is a potent CYP3A4 inducer and concomitant administration with caspofungin acetate for injection is expected to reduce the plasma concentrations of caspofungin acetate for injection. (notice Caspofungine, Interactions médicamenteuses)

  • Armodafinilstimulant du SNCModérée

    Inducers of Hepatic CYP Enzymes Rifampin : Rifampin is a potent CYP3A4 inducer and concomitant administration with caspofungin acetate for injection is expected to reduce the plasma concentrations of caspofungin acetate for injection. (notice Caspofungine, Interactions médicamenteuses)

  • Bosentaninducteur du CYP3A4Modérée

    Inducers of Hepatic CYP Enzymes Rifampin : Rifampin is a potent CYP3A4 inducer and concomitant administration with caspofungin acetate for injection is expected to reduce the plasma concentrations of caspofungin acetate for injection. (notice Caspofungine, Interactions médicamenteuses)

  • CarbamazépineanticonvulsivantModérée

    …When Caspofungin acetate for Injection is co-administered to adult patients with other inducers of hepatic CYP enzymes, such as efavirenz, nevirapine, phenytoin, dexamethasone, or carbamazepine, administration of a daily dose of 70 mg of Caspofungin acetate for Injection should be considered [see Dosage and Administration ( 2.5 ) and Clinical Pharmacology ( 12.3… (notice Caspofungine, Interactions médicamenteuses)

  • CénobamateanticonvulsivantModérée

    Inducers of Hepatic CYP Enzymes Rifampin : Rifampin is a potent CYP3A4 inducer and concomitant administration with caspofungin acetate for injection is expected to reduce the plasma concentrations of caspofungin acetate for injection. (notice Caspofungine, Interactions médicamenteuses)

  • CiclosporineimmunosuppresseurModérée

    • Elevated Liver Enzymes during Concomitant use with Cyclosporine: Limit use to patients for whom potential benefit outweighs potential risk. (notice Caspofungine, Mises en garde et précautions)

  • ClobazambenzodiazépineModérée

    Inducers of Hepatic CYP Enzymes Rifampin : Rifampin is a potent CYP3A4 inducer and concomitant administration with caspofungin acetate for injection is expected to reduce the plasma concentrations of caspofungin acetate for injection. (notice Caspofungine, Interactions médicamenteuses)

  • Déférasiroxsupplément de ferModérée

    Inducers of Hepatic CYP Enzymes Rifampin : Rifampin is a potent CYP3A4 inducer and concomitant administration with caspofungin acetate for injection is expected to reduce the plasma concentrations of caspofungin acetate for injection. (notice Caspofungine, Interactions médicamenteuses)

  • DexaméthasonecorticoïdeModérée

    …Enzymes Adults : When Caspofungin acetate for Injection is co-administered to adult patients with other inducers of hepatic CYP enzymes, such as efavirenz, nevirapine, phenytoin, dexamethasone, or carbamazepine, administration of a daily dose of 70 mg of Caspofungin acetate for Injection should be considered [see Dosage and Administration ( 2.5 ) and Clinical… (notice Caspofungine, Interactions médicamenteuses)

  • ÉfavirenzantirétroviralModérée

    Other Inducers of Hepatic CYP Enzymes Adults : When Caspofungin acetate for Injection is co-administered to adult patients with other inducers of hepatic CYP enzymes, such as efavirenz, nevirapine, phenytoin, dexamethasone, or carbamazepine, administration of a daily dose of 70 mg of Caspofungin acetate for Injection should be considered [see Dosage and Administration… (notice Caspofungine, Interactions médicamenteuses)

  • Éfavirenz, lamivudine et ténofovirantirétroviralModérée

    Other Inducers of Hepatic CYP Enzymes Adults : When Caspofungin acetate for Injection is co-administered to adult patients with other inducers of hepatic CYP enzymes, such as efavirenz, nevirapine, phenytoin, dexamethasone, or carbamazepine, administration of a daily dose of 70 mg of Caspofungin acetate for Injection should be considered [see Dosage and Administration… (notice Caspofungine, Interactions médicamenteuses)

  • EslicarbazépineanticonvulsivantModérée

    Inducers of Hepatic CYP Enzymes Rifampin : Rifampin is a potent CYP3A4 inducer and concomitant administration with caspofungin acetate for injection is expected to reduce the plasma concentrations of caspofungin acetate for injection. (notice Caspofungine, Interactions médicamenteuses)

  • ÉtravirineantirétroviralModérée

    Inducers of Hepatic CYP Enzymes Rifampin : Rifampin is a potent CYP3A4 inducer and concomitant administration with caspofungin acetate for injection is expected to reduce the plasma concentrations of caspofungin acetate for injection. (notice Caspofungine, Interactions médicamenteuses)

  • FosphénytoïneanticonvulsivantModérée

    Inducers of Hepatic CYP Enzymes Rifampin : Rifampin is a potent CYP3A4 inducer and concomitant administration with caspofungin acetate for injection is expected to reduce the plasma concentrations of caspofungin acetate for injection. (notice Caspofungine, Interactions médicamenteuses)

  • GriséofulvineantifongiqueModérée

    Inducers of Hepatic CYP Enzymes Rifampin : Rifampin is a potent CYP3A4 inducer and concomitant administration with caspofungin acetate for injection is expected to reduce the plasma concentrations of caspofungin acetate for injection. (notice Caspofungine, Interactions médicamenteuses)

  • Lopinavir et ritonavirantirétroviralModérée

    Inducers of Hepatic CYP Enzymes Rifampin : Rifampin is a potent CYP3A4 inducer and concomitant administration with caspofungin acetate for injection is expected to reduce the plasma concentrations of caspofungin acetate for injection. (notice Caspofungine, Interactions médicamenteuses)

  • Lorlatinibinducteur du CYP3A4Modérée

    Inducers of Hepatic CYP Enzymes Rifampin : Rifampin is a potent CYP3A4 inducer and concomitant administration with caspofungin acetate for injection is expected to reduce the plasma concentrations of caspofungin acetate for injection. (notice Caspofungine, Interactions médicamenteuses)

  • Mitapivatinducteur du CYP3A4Modérée

    Inducers of Hepatic CYP Enzymes Rifampin : Rifampin is a potent CYP3A4 inducer and concomitant administration with caspofungin acetate for injection is expected to reduce the plasma concentrations of caspofungin acetate for injection. (notice Caspofungine, Interactions médicamenteuses)

  • Mitotaneinducteur du CYP3A4Modérée

    Inducers of Hepatic CYP Enzymes Rifampin : Rifampin is a potent CYP3A4 inducer and concomitant administration with caspofungin acetate for injection is expected to reduce the plasma concentrations of caspofungin acetate for injection. (notice Caspofungine, Interactions médicamenteuses)

  • Modafinilstimulant du SNCModérée

    Inducers of Hepatic CYP Enzymes Rifampin : Rifampin is a potent CYP3A4 inducer and concomitant administration with caspofungin acetate for injection is expected to reduce the plasma concentrations of caspofungin acetate for injection. (notice Caspofungine, Interactions médicamenteuses)

  • Nafcillineantibiotique de la famille des pénicillinesModérée

    Inducers of Hepatic CYP Enzymes Rifampin : Rifampin is a potent CYP3A4 inducer and concomitant administration with caspofungin acetate for injection is expected to reduce the plasma concentrations of caspofungin acetate for injection. (notice Caspofungine, Interactions médicamenteuses)

  • NévirapineantirétroviralModérée

    …Inducers of Hepatic CYP Enzymes Adults : When Caspofungin acetate for Injection is co-administered to adult patients with other inducers of hepatic CYP enzymes, such as efavirenz, nevirapine, phenytoin, dexamethasone, or carbamazepine, administration of a daily dose of 70 mg of Caspofungin acetate for Injection should be considered [see Dosage and Administration… (notice Caspofungine, Interactions médicamenteuses)

  • OxcarbazépineanticonvulsivantModérée

    Inducers of Hepatic CYP Enzymes Rifampin : Rifampin is a potent CYP3A4 inducer and concomitant administration with caspofungin acetate for injection is expected to reduce the plasma concentrations of caspofungin acetate for injection. (notice Caspofungine, Interactions médicamenteuses)

  • PhénobarbitalbarbituriqueModérée

    Inducers of Hepatic CYP Enzymes Rifampin : Rifampin is a potent CYP3A4 inducer and concomitant administration with caspofungin acetate for injection is expected to reduce the plasma concentrations of caspofungin acetate for injection. (notice Caspofungine, Interactions médicamenteuses)

  • Phentermine et topiramatestimulant du SNCModérée

    Inducers of Hepatic CYP Enzymes Rifampin : Rifampin is a potent CYP3A4 inducer and concomitant administration with caspofungin acetate for injection is expected to reduce the plasma concentrations of caspofungin acetate for injection. (notice Caspofungine, Interactions médicamenteuses)

  • PhénytoïneanticonvulsivantModérée

    …Hepatic CYP Enzymes Adults : When Caspofungin acetate for Injection is co-administered to adult patients with other inducers of hepatic CYP enzymes, such as efavirenz, nevirapine, phenytoin, dexamethasone, or carbamazepine, administration of a daily dose of 70 mg of Caspofungin acetate for Injection should be considered [see Dosage and Administration ( 2.5 )… (notice Caspofungine, Interactions médicamenteuses)

  • PrimidoneanticonvulsivantModérée

    Inducers of Hepatic CYP Enzymes Rifampin : Rifampin is a potent CYP3A4 inducer and concomitant administration with caspofungin acetate for injection is expected to reduce the plasma concentrations of caspofungin acetate for injection. (notice Caspofungine, Interactions médicamenteuses)

  • RifabutineantibiotiqueModérée

    Inducers of Hepatic CYP Enzymes Rifampin : Rifampin is a potent CYP3A4 inducer and concomitant administration with caspofungin acetate for injection is expected to reduce the plasma concentrations of caspofungin acetate for injection. (notice Caspofungine, Interactions médicamenteuses)

  • RifapentineantibiotiqueModérée

    Inducers of Hepatic CYP Enzymes Rifampin : Rifampin is a potent CYP3A4 inducer and concomitant administration with caspofungin acetate for injection is expected to reduce the plasma concentrations of caspofungin acetate for injection. (notice Caspofungine, Interactions médicamenteuses)

  • RitonavirantirétroviralModérée

    Inducers of Hepatic CYP Enzymes Rifampin : Rifampin is a potent CYP3A4 inducer and concomitant administration with caspofungin acetate for injection is expected to reduce the plasma concentrations of caspofungin acetate for injection. (notice Caspofungine, Interactions médicamenteuses)

  • Suzétrigineinducteur du CYP3A4Modérée

    Inducers of Hepatic CYP Enzymes Rifampin : Rifampin is a potent CYP3A4 inducer and concomitant administration with caspofungin acetate for injection is expected to reduce the plasma concentrations of caspofungin acetate for injection. (notice Caspofungine, Interactions médicamenteuses)

  • TacrolimusimmunosuppresseurModérée

    Tacrolimus : For patients receiving Caspofungin acetate for Injection and tacrolimus, standard monitoring of tacrolimus trough whole blood concentrations and appropriate tacrolimus dosage adjustments are recommended. (notice Caspofungine, Interactions médicamenteuses)

  • TopiramateanticonvulsivantModérée

    Inducers of Hepatic CYP Enzymes Rifampin : Rifampin is a potent CYP3A4 inducer and concomitant administration with caspofungin acetate for injection is expected to reduce the plasma concentrations of caspofungin acetate for injection. (notice Caspofungine, Interactions médicamenteuses)

Vérifiez Caspofungine avec tout ce que vous prenez. Ajoutez votre liste complète ; toutes les paires sont vérifiées en une fois.

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Ceci n'est pas un avis médical. Le niveau de gravité reflète la formulation de la notice, pas votre situation. Une alerte « majeure » peut être courante sous surveillance et une alerte « mineure » peut compter à forte dose. Demandez conseil à un pharmacien.