Trinitrine : interactions médicamenteuses
Trinitrine (Nitrostat, Nitro-Dur, Nitrolingual), dérivé nitré, présente 131 interactions documentées dans les notices FDA et les fiches d'information que nous indexons : 13 de niveau majeur, 111 de niveau modéré, 7 de niveau mineur et 0 cas où une notice ne signale aucune interaction significative. Chaque entrée ci-dessous cite la phrase sur laquelle elle repose. Cette page consacrée à un médicament est un point de départ, pas un verdict sur votre situation.
Interactions d'après la notice
Interactions majeures (13)
Use of phosphodiesterase type 5 (PDE-5) Inhibitors, such as avanafil, sildenafil, tadalafil, or vardenafil, or soluble guanylate cyclase (sGC) stimulator (riociguat). (notice Trinitrine, Contre-indications)
Therefore, patients receiving sublingual nitroglycerin should avoid ergotamine and related drugs or be monitored for symptoms of ergotism if this is not possible. (notice Trinitrine, Interactions médicamenteuses)
Therefore, patients receiving sublingual nitroglycerin should avoid ergotamine and related drugs or be monitored for symptoms of ergotism if this is not possible. (notice Trinitrine, Interactions médicamenteuses)
Therefore, patients receiving sublingual nitroglycerin should avoid ergotamine and related drugs or be monitored for symptoms of ergotism if this is not possible. (notice Trinitrine, Interactions médicamenteuses)
Hypersensitivity to Nitroglycerin Lingual Spray or to other nitrates or nitrites or any excipient. (notice Trinitrine, Contre-indications)
Hypersensitivity to Nitroglycerin Lingual Spray or to other nitrates or nitrites or any excipient. (notice Trinitrine, Contre-indications)
Therefore, patients receiving sublingual nitroglycerin should avoid ergotamine and related drugs or be monitored for symptoms of ergotism if this is not possible. (notice Trinitrine, Interactions médicamenteuses)
Therefore, patients receiving sublingual nitroglycerin should avoid ergotamine and related drugs or be monitored for symptoms of ergotism if this is not possible. (notice Trinitrine, Interactions médicamenteuses)
Hypersensitivity to Nitroglycerin Lingual Spray or to other nitrates or nitrites or any excipient. (notice Trinitrine, Contre-indications)
Use of phosphodiesterase type 5 (PDE-5) Inhibitors, such as avanafil, sildenafil, tadalafil, or vardenafil, or soluble guanylate cyclase (sGC) stimulator (riociguat). (notice Trinitrine, Contre-indications)
Use of phosphodiesterase type 5 (PDE-5) Inhibitors, such as avanafil, sildenafil, tadalafil, or vardenafil, or soluble guanylate cyclase (sGC) stimulator (riociguat). (notice Trinitrine, Contre-indications)
Use of phosphodiesterase type 5 (PDE-5) Inhibitors, such as avanafil, sildenafil, tadalafil, or vardenafil, or soluble guanylate cyclase (sGC) stimulator (riociguat). (notice Trinitrine, Contre-indications)
Use of phosphodiesterase type 5 (PDE-5) Inhibitors, such as avanafil, sildenafil, tadalafil, or vardenafil, or soluble guanylate cyclase (sGC) stimulator (riociguat). (notice Trinitrine, Contre-indications)
Interactions modérées (111)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Hypotension Adenosine injection is a potent peripheral vasodilator and can induce significant hypotension. (notice Adénosine, Mises en garde et précautions)
Postural hypotension/syncope: Care should be taken in patients with symptomatic hypotension or who have had a hypotensive response to other medications or are concomitantly treated with antihypertensive medication or nitrates ( 5.1 ) (notice Alfuzosine, Mises en garde et précautions)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Examples of Drugs Associated with Methemoglobinemia: Class Examples Nitrates/Nitrites nitric oxide, nitroglycerin, nitroprusside, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine, tetracaine Antineoplastic agents cyclophosphamide, flutamide, hydroxyurea, ifosfamide, rasburicase Antibiotics… (notice Articaïne et adrénaline, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives Patients receiving antihypertensive drugs, beta-adrenergic blockers, and nitrates should be observed for possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
• Drugs Associated with Methemoglobinemia : Patients are at increased risk of developing methemoglobinemia when concurrently exposed to nitrates, nitrites, local anesthetics, antineoplastic agents, antibiotics, antimalarials, anticonvulsants, and other drugs. (notice Bupivacaïne, Interactions médicamenteuses)
Examples of Drugs Associated with Methemoglobinemia: Class Examples Nitrates/Nitrites nitric oxide, nitroglycerin, nitroprusside, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine, tetracaine Antineoplastic agents cyclophosphamide, flutamide, hydroxyurea, ifosfamide, rasburicase Antibiotics… (notice Bupivacaïne et adrénaline, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
…concurrently exposed to the following drugs, which could include other local anesthetics: Examples of Drugs Associated with Methemoglobinemia: Class Examples Nitrates/Nitrites nitric oxide, nitroglycerin, nitroprusside, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine, tetracaine Antineoplastic… (notice Chloroprocaïne, Précautions)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
• Co-administration with Other Vasodilators or Negative Chronotropic Agents : Use with caution due to additive pharmacodynamic effects. (notice Dexmédétomidine, Mises en garde et précautions)
…drugs including dicyclomine hydrochloride: amantadine, antiarrhythmic agents of Class I (e.g., quinidine), antihistamines, antipsychotic agents (e.g., phenothiazines), benzodiazepines, MAO inhibitors, narcotic analgesics (e.g., meperidine), nitrates and nitrites, sympathomimetic agents, tricyclic antidepressants, and other drugs having anticholinergic activity. (notice Dicyclovérine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
…oral anticoagulants, calcium channel blockers, beta blockers, cardiac glycosides, inducers of CYP3A4, substrates and inhibitors of CYP3A4, substrates and inhibitors of P-glycoprotein, nitrates, sulphonylureas, loop diuretics, potassium sparing diuretics, thiazide diuretics, substrates and inhibitors of tubular organic cation transport, and QTc-prolonging drugs. (notice Dofétilide, Interactions médicamenteuses)
Antihypertensives Patients receiving antihypertensive drugs, beta-adrenergic blockers, and nitrates should be observed for possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Most cases reported product application with use under occlusion, genital application, or application to a large body surface area which may increase the systemic absorption of econazole nitrate. (notice Éconazole, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Additional reductions in blood pressure may occur when VELETRI is administered with diuretics, antihypertensive agents, or other vasodilators. (notice Époprosténol, Interactions médicamenteuses)
Antihypertensives Patients receiving antihypertensive drugs, beta-adrenergic blockers, and nitrates should be observed for possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Co-administration of vaginal miconazole nitrate and Etonogestrel/Ethinyl Estradiol Vaginal Ring increases the serum concentrations of etonogestrel and ethinyl estradiol by up to 40% [see Clinical Pharmacology (12.3) ] . (notice Étonogestrel et éthinylestradiol, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Intravenous nitroglycerin administered to heparinized patients may result in a decrease of the partial thromboplastin time with subsequent rebound effect upon discontinuation of nitroglycerin. (notice Héparine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Examples of Drugs Associated with Methemoglobinemia: Class Examples Nitrates/Nitrites nitric oxide, nitroglycerin, nitroprusside, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine, tetracaine Antineoplastic agents cyclophosphamide, flutamide, hydroxyurea, isofamide, rasburicase Antibiotics… (notice Lidocaïne et adrénaline, Interactions médicamenteuses)
…concurrently exposed to the following drugs, which could include other local anesthetics: Examples of Drugs Associated with Methemoglobinemia: Class Examples Nitrates/Nitrites nitric oxide, nitroglycerin, nitroprusside, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine, tetracaine Antineoplastic… (notice Lidocaïne et prilocaïne, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
…when concurrently exposed to the following drugs, which could include other local anesthetics: Examples of Drugs Associated with Methemoglobinemia: Class Examples Nitrates/Nitrites nitroglycerin, nitroprusside, nitric oxide, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine, tetracaine… (notice Mépivacaïne, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
- NiacineModérée
Caution should also be used when niacin extended-release tablets are used in patients with unstable angina or in the acute phase of an MI, particularly when such patients are also receiving vasoactive drugs such as nitrates, calcium channel blockers, or adrenergic blocking agents. (notice Niacine, Mises en garde et précautions)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Marked orthostatic hypotension has been reported when calcium channel blockers and organic nitrates were used concomitantly. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
- Olmésartan, amlodipine et hydrochlorothiazideantagoniste des récepteurs de l'angiotensine II (ARA II)Modérée
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
…concurrently exposed to the following drugs, which could include other local anesthetics: EXAMPLES OF DRUGS ASSOCIATED WITH METHEMOGLOBINEMIA: Class Examples Nitrates/Nitrites nitric oxide, nitroglycerin, nitroprusside, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine, tetracaine Antineoplastic… (notice Prilocaïne et adrénaline, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
…which could include other local anesthetics [see Warnings and Precautions ( 5.4 )] : Examples of Drugs Associated with Methemoglobinemia Class Examples Nitrates/Nitrites nitric oxide, nitroglycerin, nitroprusside, nitrous oxide Local anesthetics articaine, benzocaine, bupivacaine, lidocaine, mepivacaine, prilocaine, procaine, ropivacaine, tetracaine Antineoplastic… (notice Ropivacaïne, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives Patients receiving antihypertensive drugs, beta-adrenergic blockers, and nitrates should be observed for possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives Patients receiving antihypertensive drugs, beta-adrenergic blockers, and nitrates should be observed for possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Antihypertensives: Possible additive hypotensive effects. (notice Trinitrine, Interactions médicamenteuses)
Mentions mineures (7)
Drugs antagonizing pressor effects of epinephrine α-blockers, such as phentolamine Vasodilators, such as nitrates Diuretics Antihypertensives Ergot alkaloids Drugs potentiating pressor effects of epinephrine • Sympathomimetics • β-blockers, such as propranolol • Tricyclic anti-depressants • Monoamine oxidase (MAO) inhibitors • Catechol-O-methyl transferase (COMT)… (notice Adrénaline, Interactions médicamenteuses)
Alpha-adrenergic antagonists and PDE-5 inhibitors are both vasodilators that can lower blood pressure. (notice Dutastéride et tamsulosine, Mises en garde et précautions)
…acetylsalicylic acid, α-blockers, angiotensin-converting enzyme (ACE) inhibitors, analgesics, anti-convulsants, beta-adrenergic blocking agents, diuretics, calcium channel blockers, cardiac nitrates, HMG-CoA reductase inhibitors, nonsteroidal anti-inflammatory drugs (NSAIDs), benzodiazepines, H 2 antagonists and quinolone anti-infectives without evidence of clinically… (notice Finastéride, Interactions médicamenteuses)
Post injury arterial injection of vasodilators and/or arterial infusion of parenteral fluids are generally regarded to be of no value in altering outcome. (notice Méthohexital, Mises en garde)
…been observed in limited experience with patients in whom milrinone was used concurrently with the following drugs: digitalis glycosides; lidocaine, quinidine; hydralazine, prazosin; isosorbide dinitrate, nitroglycerin; chlorthalidone, furosemide, hydrochlorothiazide, spironolactone; captopril; heparin, warfarin, diazepam, insulin; and potassium supplements. (notice Milrinone, Interactions médicamenteuses)
Alpha-adrenergic blockers and PDE5 inhibitors are both vasodilators that can lower blood pressure. (notice Silodosine, Mises en garde et précautions)
Alpha-adrenergic blockers and PDE5 inhibitors are both vasodilators that can lower blood pressure. (notice Tamsulosine, Mises en garde et précautions)
Vérifiez Trinitrine avec tout ce que vous prenez. Ajoutez votre liste complète ; toutes les paires sont vérifiées en une fois.
Ouvrir dans le vérificateurCeci n'est pas un avis médical. Le niveau de gravité reflète la formulation de la notice, pas votre situation. Une alerte « majeure » peut être courante sous surveillance et une alerte « mineure » peut compter à forte dose. Demandez conseil à un pharmacien.