Prucalopride : interactions médicamenteuses

Prucalopride (Motegrity), médicament sérotoninergique, présente 64 interactions documentées dans les notices FDA et les fiches d'information que nous indexons : 56 de niveau majeur, 2 de niveau modéré, 6 de niveau mineur et 0 cas où une notice ne signale aucune interaction significative. Chaque entrée ci-dessous cite la phrase sur laquelle elle repose. Cette page consacrée à un médicament est un point de départ, pas un verdict sur votre situation.

Interactions d'après la notice

Interactions majeures (56)

  • Amphétaminestimulant du SNCMajeure

    Serotonin Syndrome: Increased risk when co-administered with serotonergic agents (e.g., SSRIs, SNRIs, triptans), but also during overdosage situations. (notice Amphétamine, Mises en garde et précautions)

  • Amphétamine et dexamfétaminestimulant du SNCMajeure

    Serotonin Syndrome: Increased risk when coadministered with serotonergic agents (e.g., selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), triptans), but also during overdosage situations. (notice Amphétamine et dexamfétamine, Mises en garde et précautions)

  • Belladone et opiumopioïdeMajeure

    • Serotonergic Drugs: Concomitant use may result in serotonin syndrome. (notice Belladone et opium, Interactions médicamenteuses)

  • Clinically significant drug interactions with PROVAYBLUE are described below: The concomitant use of PROVAYBLUE with other drugs that affect the serotonergic neurotransmitter system has resulted in serotonin syndrome. (notice Bleu de méthylène, Interactions médicamenteuses)

  • BuprénorphineopioïdeMajeure

    Serotonergic Drugs : Concomitant use may result in serotonin syndrome. (notice Buprénorphine, Interactions médicamenteuses)

  • Serotonergic Drugs: Concomitant use may result in serotonin syndrome. (notice Buprénorphine et naloxone, Interactions médicamenteuses)

  • Buspironemédicament sérotoninergiqueMajeure

    Serotonin Syndrome The development of a potentially life-threatening serotonin syndrome has been reported with SNRIs SSRIs, and other serotonergic drugs, including buspirone, alone but particularly with concomitant use of other serotonergic drugs (including triptans), with drugs that impair metabolism of serotonin (in particular, MAOIs, including reversible MAOIs… (notice Buspirone, Mises en garde)

  • Intervention: Avoid concomitant use Serotonergic Drugs : Concomitant use may result in serotonin syndrome. (notice Butalbital, aspirine, caféine et codéine, Interactions médicamenteuses)

  • • Serotonergic Drugs: Concomitant use may result in serotonin syndrome. (notice Butalbital, paracétamol, caféine et codéine, Interactions médicamenteuses)

  • ButorphanolopioïdeMajeure

    …medical attention if they ‎experience symptoms of hyperalgesia, including worsening pain, increased ‎sensitivity to pain, or new pain [see WARNINGS ; ADVERSE REACTIONS ].‎ Serotonin Syndrome Inform patients that butorphanol tartrate could cause a rare but potentially life-threatening condition resulting from concomitant administration of serotonergic drugs. (notice Butorphanol, Précautions)

  • CitalopramISRSMajeure

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (notice Citalopram, Mises en garde et précautions)

  • CodéineopioïdeMajeure

    • Serotonergic Drugs: Concomitant use may result in serotonin syndrome. (notice Codéine, Interactions médicamenteuses)

  • CyclobenzaprinemyorelaxantMajeure

    If serotonin syndrome symptoms occur with the use of other serotonergic drugs, immediately discontinue TONMYA. (notice Cyclobenzaprine, Interactions médicamenteuses)

  • DesvenlafaxineIRSNaMajeure

    • Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (notice Desvenlafaxine, Mises en garde et précautions)

  • Dexamfétaminestimulant du SNCMajeure

    Serotonin Syndrome Serotonin syndrome, a potentially life-threatening reaction, may occur when amphetamines are used in combination with other drugs that affect the serotonergic neurotransmitter systems such as monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), triptans,… (notice Dexamfétamine, Mises en garde)

  • DuloxétineIRSNaMajeure

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (notice Duloxétine, Mises en garde et précautions)

  • EscitalopramISRSMajeure

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone. (notice Escitalopram, Mises en garde et précautions)

  • FentanylopioïdeMajeure

    • Serotonin Syndrome : Potentially life-threatening condition could result from concomitant serotonergic drug administration. (notice Fentanyl, Mises en garde et précautions)

  • FluoxétineISRSMajeure

    If concomitant use of PROZAC with other serotonergic drugs is clinically warranted, patients should be made aware of a potential increased risk for serotonin syndrome, particularly during treatment initiation and dose increases ( 5.2 ) (notice Fluoxétine, Mises en garde et précautions)

  • FluvoxamineISRSMajeure

    If concomitant use of Fluvoxamine Maleate Tablets with other serotonergic drugs is clinically warranted, patients should be made aware of a potential increased risk for serotonin syndrome, particularly during treatment initiation and dose increases. (notice Fluvoxamine, Mises en garde et précautions)

  • Granisétronmédicament allongeant l'intervalle QTMajeure

    Patients should be monitored for the emergence of serotonin syndrome, especially with concomitant use of granisetron and other serotonergic drugs. (notice Granisétron, Mises en garde et précautions)

  • HydrocodoneopioïdeMajeure

    Example: lactulose Serotonergic Drugs : Concomitant use may result in serotonin syndrome. (notice Hydrocodone, Interactions médicamenteuses)

  • Serotonergic drugs : Concomitant use may result in serotonin syndrome. (notice Hydrocodone et chlorphénamine, Interactions médicamenteuses)

  • Serotonergic Drugs : Concomitant use may result in serotonin syndrome. (notice Hydrocodone et homatropine, Interactions médicamenteuses)

  • S er otonin Syndrome Inform patients that opioids could cause a rare but potentially life-threatening condition resulting from concomitant administration of serotonergic drugs. (notice Hydrocodone et ibuprofène, Précautions)

  • Serotonin Syndrome Inform patients that hydrocodone bitartrate and acetaminophen tablets could cause a rare but potentially life-threatening condition resulting from concomitant administration of serotonergic drugs. (notice Hydrocodone et paracétamol, Précautions)

  • HydromorphoneopioïdeMajeure

    • Serotonergic Drugs : Concomitant use may result in serotonin syndrome. (notice Hydromorphone, Interactions médicamenteuses)

  • LévomilnacipranIRSNaMajeure

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (notice Lévomilnacipran, Mises en garde et précautions)

  • LévorphanolopioïdeMajeure

    Serotonin Syndrome Inform patients that opioids could cause a rare but potentially life-threatening condition resulting from concomitant administration of serotonergic drugs. (notice Lévorphanol, Précautions)

  • Lisdexamfétaminestimulant du SNCMajeure

    Serotonin Syndrome: Increased risk when co-administered with serotonergic agents (e.g., SSRIs, SNRIs, triptans), but also during overdosage situations. (notice Lisdexamfétamine, Mises en garde et précautions)

  • Lithiummédicament sérotoninergiqueMajeure

    If concomitant use of lithium with other serotonergic drugs is clinically warranted, inform patients of the increased risk for serotonin syndrome and monitor for symptoms. (notice Lithium, Mises en garde et précautions)

  • MétaxalonemyorelaxantMajeure

    Serotonin syndrome has resulted from concomitant use of metaxalone (within the recommended dosage range) and other serotonergic drugs [see Warnings and Precautions (5.1) ]. (notice Métaxalone, Interactions médicamenteuses)

  • MéthadoneopioïdeMajeure

    Serotonin Syndrome : Potentially life-threatening condition could result from concomitant serotonergic drug administration. (notice Méthadone, Mises en garde et précautions)

  • Méthamphétaminestimulant du SNCMajeure

    Serotonin Syndrome: Increased risk when coadministered with serotonergic agents (e.g., SSRIs, SNRIs, triptans), but also during overdosage situations. (notice Méthamphétamine, Mises en garde et précautions)

  • MillepertuisPlantes et compléments alimentairesMajeure

    L'association du millepertuis avec des antidépresseurs et d'autres médicaments sérotoninergiques augmente le risque de syndrome sérotoninergique. (NCCIH, St. John's Wort)

  • MilnacipranIRSNaMajeure

    • Serotonin Syndrome : Increased risk when co-administered with other serotonergic agents, but also when taken alone. (notice Milnacipran, Mises en garde et précautions)

  • MirtazapineantidépresseurMajeure

    Serotonin Syndrome : Increased risk when co-administered with other serotonergic drugs (e.g., SSRI, SNRI, triptans), but also when taken alone. (notice Mirtazapine, Mises en garde et précautions)

  • MorphineopioïdeMajeure

    • Serotonergic Drugs: Concomitant use may result in serotonin syndrome. (notice Morphine, Interactions médicamenteuses)

  • Olanzapine et fluoxétineantipsychotiqueMajeure

    If concomitant use of olanzapine and fluoxetine capsules with other serotonergic drugs is clinically warranted, patients should be made aware of a potential increased risk for serotonin syndrome, particularly during treatment initiation and dose increases ( 5.6 ) (notice Olanzapine et fluoxétine, Mises en garde et précautions)

  • OlicéridineopioïdeMajeure

    Serotonergic Drugs : Concomitant use may result in serotonin syndrome. (notice Olicéridine, Interactions médicamenteuses)

  • Ondansétronmédicament allongeant l'intervalle QTMajeure

    Patients should be monitored for the emergence of serotonin syndrome, especially with concomitant use of Ondansetron Injection and other serotonergic drugs. (notice Ondansétron, Mises en garde et précautions)

  • OxycodoneopioïdeMajeure

    Serotonergic Drug s: Concomitant use may result in serotonin syndrome. (notice Oxycodone, Interactions médicamenteuses)

  • OxymorphoneopioïdeMajeure

    Serotonergic Drugs : Concomitant use may result in serotonin syndrome. (notice Oxymorphone, Interactions médicamenteuses)

  • Palonosétronmédicament sérotoninergiqueMajeure

    Patients should be monitored for the emergence of serotonin syndrome, especially with concomitant use of POSFREA and other serotonergic drugs. (notice Palonosétron, Mises en garde et précautions)

  • Serotonin Syndrome Inform patients that opioids could cause a rare but potentially life-threatening condition resulting from concomitant administration of serotonergic drugs. (notice Paracétamol et codéine, Précautions)

  • ParoxétineISRSMajeure

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (notice Paroxétine, Mises en garde et précautions)

  • Serotonin Syndrome Inform patients that opioids could cause a rare but potentially life-threatening condition resulting from concomitant administration of serotonergic drugs. (notice Pentazocine et naloxone, Précautions)

  • Serotonergic Drugs : Concomitant use may result in serotonin syndrome. (notice Prométhazine et codéine, Interactions médicamenteuses)

  • RémifentanilopioïdeMajeure

    • Serotonin Syndrome : Potentially life-threatening condition could result from concomitant serotonergic drug administration. (notice Rémifentanil, Mises en garde et précautions)

  • SertralineISRSMajeure

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (notice Sertraline, Mises en garde et précautions)

  • TranylcypromineIMAOMajeure

    Serotonin Syndrome The development of a potentially life-threatening serotonin syndrome has been reported with MAOIs when used concomitantly with other serotonergic drugs. (notice Tranylcypromine, Mises en garde et précautions)

  • TrazodoneantidépresseurMajeure

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents (e.g., SSRI, SNRI, triptans), but also when taken alone. (notice Trazodone, Mises en garde et précautions)

  • VenlafaxineIRSNaMajeure

    If concomitant use of Venlafaxine Extended Release Tablets with other serotonergic drugs is clinically warranted, patients should be made aware of a potential increased risk for serotonin syndrome, particularly during treatment initiation and dose increases. (notice Venlafaxine, Mises en garde et précautions)

  • VilazodoneISRSMajeure

    Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. (notice Vilazodone, Mises en garde et précautions)

  • VortioxétineantidépresseurMajeure

    • Serotonin Syndrome : Increased risk when coadministered with other serotonergic agents, but also when taken alone. (notice Vortioxétine, Mises en garde et précautions)

  • ZiprasidoneantipsychotiqueMajeure

    • Serotonin Syndrome : Increased risk when co-administered with other serotonergic agents, but also when taken alone. (notice Ziprasidone, Mises en garde et précautions)

Interactions modérées (2)

  • NalbuphineopioïdeModérée

    Serotonergic Drugs The concomitant use of opioids with other drugs that affect the serotonergic neurotransmitter system, such as selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs), triptans, 5-HT3 receptor antagonists, drugs that effect the serotonin neurotransmitter system… (notice Nalbuphine, Interactions médicamenteuses)

  • TramadolopioïdeModérée

    …and other sedatives/hypnotics, anxiolytics, tranquilizers, muscle relaxants, general anesthetics, antipsychotics, gabapentinoids (gabapentin or pregabalin), other opioids, alcohol Serotonergic Drugs Clinical Impact: The concomitant use of opioids with other drugs that affect the serotonergic neurotransmitter system has resulted in serotonin syndrome [see Warnings… (notice Tramadol, Interactions médicamenteuses)

Mentions mineures (6)

  • Clomipramineantidépresseur tricycliqueMineure

    Serotonin Syndrome The development of a potentially life-threatening serotonin syndrome has been reported with SNRIs and SSRIs, including clomipramine hydrochloride capsules, alone but particularly with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, tryptophan, buspirone, and St. (notice Clomipramine, Mises en garde)

  • Désipramineantidépresseur tricycliqueMineure

    …Syndrome: The development of a potentially life-threatening serotonin syndrome has been reported with serotonin norepinephrine re-uptake inhibitors (SNRIs) and SSRIs, including NORPRAMIN, alone but particularly with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, tryptophan, buspirone, and St. (notice Désipramine, Mises en garde)

  • Nortriptylineantidépresseur tricycliqueMineure

    Serotonin Syndrome The development of a potentially life-threatening serotonin syndrome has been reported with SNRIs and SSRIs, including Pamelor, alone but particularly with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, tryptophan, buspirone, and St. (notice Nortriptyline, Mises en garde)

  • Serotonergic Drugs Clinical Impact: The concomitant use of opioids with other drugs that affect the serotonergic neurotransmitter system has resulted in serotonin syndrome [see Adverse Reaction ( 6.2)]. (notice Oxycodone et paracétamol, Interactions médicamenteuses)

  • Phenterminestimulant du SNCMineure

    The safety and efficacy of combination therapy with phentermine and any other drug products for weight loss including prescribed drugs, over-the-counter preparations, and herbal products, or serotonergic agents such as selective serotonin reuptake inhibitors (e.g., fluoxetine, sertraline, fluvoxamine, paroxetine), have not been established. (notice Phentermine, Mises en garde et précautions)

  • Trimipramineantidépresseur tricycliqueMineure

    Serotonin Syndrome The development of a potentially life-threatening serotonin syndrome has been reported with SNRIs and SSRIs, including trimipramine capsules, alone, but particularly with concomitant use of other serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, tryptophan, buspirone, and St. (notice Trimipramine, Mises en garde)

Vérifiez Prucalopride avec tout ce que vous prenez. Ajoutez votre liste complète ; toutes les paires sont vérifiées en une fois.

Ouvrir dans le vérificateur

Ceci n'est pas un avis médical. Le niveau de gravité reflète la formulation de la notice, pas votre situation. Une alerte « majeure » peut être courante sous surveillance et une alerte « mineure » peut compter à forte dose. Demandez conseil à un pharmacien.