Abrocitinib and Aspirin interaction

Abrocitinib and Aspirin: the Abrocitinib prescribing label flags this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

From the Abrocitinib (Cibinqo) label · effective 2026-09-09

Major

CIBINQO is contraindicated in patients taking antiplatelet therapies, except for low-dose aspirin (≤81 mg daily), during the first 3 months of treatment [see Warnings and Precautions (5.7) , Drug Interactions (7.2) , and Clinical Pharmacology (12.2) ].

Contraindicationsby drug classView label on DailyMed
Major

Antiplatelet therapies except for low-dose aspirin (≤81 mg daily), during the first 3 months of treatment.

Contraindicationsby drug classView label on DailyMed
Major

Intervention CIBINQO is contraindicated in patients taking antiplatelet drugs, except for low-dose aspirin (≤81 mg daily), during the first 3 months of treatment [see Contraindications (4) ] .

Drug interactionsby drug classView label on DailyMed
Moderate

Antiplatelet Therapy Drugs Clinical Impact Concomitant use of CIBINQO with antiplatelet therapy drugs may increase the risk of bleeding with thrombocytopenia [see Warnings and Precautions (5.5) and Clinical Pharmacology (12.2) ].

Drug interactionsby drug classView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.