Acebutolol and Furosemide interaction

Acebutolol and Furosemide: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Acebutolol (Acebutolol Hydrochloride) label · effective 2025-11-07

Moderate

Although β-blockers should be avoided in overt cardiac failure, acebutolol can be used with caution in patients with a history of heart failure who are controlled with digitalis and/or diuretics.

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Minor

At the first signs of failure, patients should be digitalized and/or be given a diuretic and the response observed closely.

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Minor

If cardiac failure continues despite adequate digitalization and/or diuretic, acebutolol therapy should be withdrawn.

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From the Furosemide label · effective 2026-05-13

Moderate

Monitor for changes in blood pressure and adjust the dose of other antihypertensive drugs if needed.

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Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.