Acetaminophen and codeine and Desogestrel and ethinyl estradiol interaction
Acetaminophen and codeine and Desogestrel and ethinyl estradiol: the Desogestrel and ethinyl estradiol prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Desogestrel and ethinyl estradiol label · effective 2026-06-24
Ascorbic acid and acetaminophen may increase plasma EE concentrations, possibly by inhibition of conjugation.
COCs have been shown to decrease plasma concentrations of acetaminophen, clofibric acid, morphine, salicylic acid, temazepam and lamotrigine.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.