Aclidinium and Olanzapine interaction

Aclidinium and Olanzapine: both prescribing labels flag this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

From the Aclidinium (Tudorza Pressair) label · effective 2022-08-01

Major

Avoid administrations of TUDORZA PRESSAIR with other anticholinergic-containing drugs.

Drug interactionsby drug classView label on DailyMed
Major

Therefore, avoid coadministration of TUDORZA PRESSAIR with other anticholinergic-containing drugs as this may lead to an increase in anticholinergic effects.

Drug interactionsby drug classView label on DailyMed

From the Olanzapine (Zyprexa) label · effective 2026-02-11

Moderate

Anticholinergic (antimuscarinic) Effects: Use with caution with other anticholinergic drugs and in patients with urinary retention, prostatic hypertrophy, constipation, paralytic ileus or related conditions.

Warnings and precautionsby drug classView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.