Albendazole and Praziquantel interaction

Albendazole and Praziquantel: the Albendazole prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Albendazole (ALBENZA) label · effective 2019-09-23

Moderate

Praziquantel: In the fed state increased mean maximum plasma concentration and area under the curve of albendazole sulfoxide by about 50% in healthy subjects.

Drug interactionsnames PraziquantelView label on DailyMed
Moderate

Praziquantel In the fed state, praziquantel (40 mg/kg) increased mean maximum plasma concentration and area under the curve of albendazole sulfoxide by about 50% in healthy subjects (n = 10) compared with a separate group of subjects (n = 6) given albendazole alone.

Drug interactionsnames PraziquantelView label on DailyMed
Minor

The pharmacokinetics of praziquantel were unchanged following co-administration with albendazole (400 mg).

Drug interactionsnames PraziquantelView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.