Alcohol and Alprostadil interaction

Alcohol and Alprostadil: the Alprostadil prescribing label flags this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

From the Alprostadil (Caverject) label · effective 2024-05-13

Major

• Benzyl alcohol: Serious and fatal adverse reactions can occur in neonates and low birth weight infants treated with benzyl alcohol-preserved formulations in infusion solutions, including CAVERJECT.

Warnings and precautionsnames AlcoholView label on DailyMed
Major

Serious and fatal adverse reactions including "gasping syndrome" can occur in neonates and low birth weight infants treated with benzyl alcohol-preserved formulations in infusion solutions, including CAVERJECT.

Warnings and precautionsnames AlcoholView label on DailyMed
Moderate

Risk of Serious Adverse Reactions in Infants due to Benzyl Alcohol Preservative When reconstituted using the recommended diluent, the solution contains benzyl alcohol.

Warnings and precautionsnames AlcoholView label on DailyMed
Minor

Compress the site of injection with an alcohol swab or sterile gauze for 5 minutes ( 5.4 ).

Warnings and precautionsnames AlcoholView label on DailyMed
Minor

Compress the site of injection with an alcohol swab or sterile gauze for 5 minutes.

Warnings and precautionsnames AlcoholView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.