Alcohol and Atropine interaction

Alcohol and Atropine: the Atropine prescribing label flags this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

From the Atropine (Atropine Sulfate) label · effective 2026-08-31

Major

Benzyl Alcohol The preservative benzyl alcohol has been associated with serious adverse events and death in neonates.

Warnings and precautionsnames AlcoholView label on DailyMed
Moderate

The "gasping syndrome"(characterized by central nervous system depression, metabolic acidosis, gasping respirations, and high levels of benzyl alcohol and its metabolites found in the blood and urine) has been associated with benzyl alcohol dosages >99 mg/kg/day in neonates and low-birth weight infants.

Warnings and precautionsnames AlcoholView label on DailyMed
Moderate

Although normal therapeutic doses of this product deliver amounts of benzyl alcohol that are substantially lower than those reported in association with the "gasping syndrome", the minimum amount of benzyl alcohol at which toxicity may occur is not known.

Warnings and precautionsnames AlcoholView label on DailyMed
Moderate

Practitioners administering this and other medications containing benzyl alcohol should consider the combined daily metabolic load of benzyl alcohol from all sources.

Warnings and precautionsnames AlcoholView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.