Alcohol and Cyclophosphamide interaction

Alcohol and Cyclophosphamide: the Cyclophosphamide prescribing label flags this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

From the Cyclophosphamide (Frindovyx) label · effective 2026-08-26

Major

Alcohol Content The alcohol content in a dose of FRINDOVYX may affect the central nervous system and should be taken into account for patients in whom alcohol intake should be avoided or minimized.

Warnings and precautionsnames AlcoholView label on DailyMed
Moderate

Alcohol content : The alcohol content in a dose of FRINDOVYX may affect the central nervous system.

Warnings and precautionsnames AlcoholView label on DailyMed
Moderate

Consideration should be given to the alcohol content in FRINDOVYX on the ability to drive or use machines immediately after the infusion.

Warnings and precautionsnames AlcoholView label on DailyMed
Minor

Each administration of FRINDOVYX at 50 mg per kg delivers 0.0448 g/kg of ethanol.

Warnings and precautionsnames AlcoholView label on DailyMed
Minor

For a 75 kg patient this would deliver 3.36 grams of ethanol [see Description (11) ] .

Warnings and precautionsnames AlcoholView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.