Alcohol and Desvenlafaxine interaction
Alcohol and Desvenlafaxine: the Desvenlafaxine prescribing label flag this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.
Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.
What the FDA labels say
From the Desvenlafaxine (Pristiq Extended-Release) label · effective 2026-04-28
However, as with all CNS-active drugs, patients should be advised to avoid alcohol consumption while taking PRISTIQ.
Alcohol A clinical study has shown that PRISTIQ does not increase the impairment of mental and motor skills caused by ethanol.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.