Alcohol and Dextromethorphan and quinidine interaction

Alcohol and Dextromethorphan and quinidine: the Dextromethorphan and quinidine prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Dextromethorphan and quinidine (Nuedexta) label · effective 2026-01-22

Moderate

Alcohol As with any other CNS drug, caution should be used when NUEDEXTA is taken in combination with other centrally acting drugs and alcohol.

Drug interactionsnames AlcoholView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.