Alcohol and Eluxadoline interaction

Alcohol and Eluxadoline: the Eluxadoline prescribing label flag this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

From the Eluxadoline (Viberzi) label · effective 2024-07-16

Major

With alcoholism, alcohol abuse or alcohol addiction, or in patients who drink more than 3 alcoholic beverages per day.

Contraindicationsnames AlcoholView label on DailyMed
Major

…gallbladder ( 4 ) known or suspected biliary duct obstruction, or sphincter of Oddi disease or dysfunction ( 4 ) alcoholism, alcohol abuse, alcohol addiction, or drink more than 3 alcoholic beverages/day ( 4 ) a history of pancreatitis; structural diseases of the pancreas, including known or suspected pancreatic duct obstruction ( 4 ) patients with a known hypersensitivity…

Contraindicationsnames AlcoholView label on DailyMed
Major

Instruct patients to avoid chronic or acute excessive alcohol use while taking VIBERZI.

Warnings and precautionsnames AlcoholView label on DailyMed
Minor

In patients with a gallbladder, evaluate a patient’s alcohol intake prior to starting VIBERZI.

Warnings and precautionsnames AlcoholView label on DailyMed

Curated guidance for Alcohol

Major

Combining alcohol with sedating medicines (opioids, benzodiazepines, sleep medicines, muscle relaxants) can cause dangerous drowsiness, slowed breathing, and overdose.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.