Alcohol and Enoxaparin interaction

Alcohol and Enoxaparin: the Enoxaparin prescribing label flag this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

From the Enoxaparin (Enoxaparin Sodium) label · effective 2026-02-04

Major

…hypersensitivity to enoxaparin sodium (e.g., pruritus, urticaria, anaphylactic/anaphylactoid reactions) [see Adverse Reactions (6.2) ] Known hypersensitivity to heparin or pork products Known hypersensitivity to benzyl alcohol (which is in only the multiple-dose formulation of enoxaparin sodium) [see Warnings and Precautions (5.8) ] Active major bleeding ( 4 )

Contraindicationsnames AlcoholView label on DailyMed
Major

Hypersensitivity to benzyl alcohol (for multiple-dose formulation only) ( 4 )

Contraindicationsnames AlcoholView label on DailyMed
Major

Serious and fatal adverse reactions including "gasping syndrome" can occur in neonates and low-birth-weight infants treated with benzyl alcohol-preserved drugs, including enoxaparin sodium multiple-dose vials.

Warnings and precautionsnames AlcoholView label on DailyMed
Moderate

Risk of Serious Adverse Reactions in Infants due to Benzyl Alcohol Preservative Enoxaparin sodium multiple-dose vials are not approved for use in neonates or infants.

Warnings and precautionsnames AlcoholView label on DailyMed
Moderate

The minimum amount of benzyl alcohol at which serious adverse reactions may occur is not known (enoxaparin sodium multiple-dose vials contain 15 mg of benzyl alcohol per mL) [see Use in Specific Populations (8.4) ].

Warnings and precautionsnames AlcoholView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.