Alcohol and Phenelzine interaction

Alcohol and Phenelzine: the Phenelzine prescribing label flag this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

From the Phenelzine (phenelzine sulfate) label · effective 2026-05-21

Major

Phenelzine sulfate should not be used in combination with dextromethorphan or with CNS depressants such as alcohol and certain narcotics.

Contraindicationsnames AlcoholView label on DailyMed
Major

…pepperoni, and Lebanon bologna) Vegetables Broad bean pods (fava bean pods) Sauerkraut Dairy Products Cheese (cottage cheese and cream cheese are allowed) Yogurt Beverages Beer and wine Alcohol-free and reduced-alcohol beer and wine products Miscellaneous Yeast extract (including brewer's yeast in large quantities) Meat extract Excessive amounts of chocolate and caffeine…

Warningsnames AlcoholView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.