Alcohol and Tiagabine interaction

Alcohol and Tiagabine: the Tiagabine prescribing label flag this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

Curated guidance for Alcohol

Major

Combining alcohol with sedating medicines (opioids, benzodiazepines, sleep medicines, muscle relaxants) can cause dangerous drowsiness, slowed breathing, and overdose.

From the Tiagabine (Tiagabine Hydrochloride) label · effective 2021-09-30

Moderate

Ethanol or Triazolam : No significant differences were observed in the pharmacokinetics of triazolam (0.125 mg) and tiagabine (10 mg) when given together as a single dose.

Drug interactionsnames AlcoholView label on DailyMed
Moderate

Because of the possible additive effects of drugs that may depress the nervous system, ethanol or triazolam should be used cautiously in combination with tiagabine.

Drug interactionsnames AlcoholView label on DailyMed
No interaction

The pharmacokinetics of ethanol were not affected by multiple-dose administration of tiagabine.

Drug interactionsnames AlcoholView label on DailyMed
No interaction

Tiagabine has shown no clinically important potentiation of the pharmacodynamic effects of triazolam or alcohol.

Drug interactionsnames AlcoholView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.