Allopurinol and Propofol interaction
Allopurinol and Propofol: the Allopurinol prescribing label describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Moderate
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Allopurinol label · effective 2026-05-21
Moderate
Inform patients also that the central nervous system depressant effects of allopurinol tablets may be additive to those of alcohol and other CNS depressants.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.