Amantadine and Phentermine interaction

Amantadine and Phentermine: the Amantadine prescribing label mentions this combination without an instruction to avoid it or change the dose.

Minor

Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.

What the FDA labels say

From the Amantadine (AMANTADINE HYDROCHLORIDE) label · effective 2026-04-08

Minor

Drug Interactions Careful observation is required when amantadine hydrochloride is administered concurrently with central nervous system stimulants.

Drug interactionsby drug classView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.