Amlodipine and Atenolol and chlorthalidone interaction

Amlodipine and Atenolol and chlorthalidone: the Atenolol and chlorthalidone prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Atenolol and chlorthalidone label · effective 2025-09-22

Moderate

Because of its relative beta 1 -selectivity, however, atenolol and chlorthalidone may be used with caution in patients with bronchospastic disease who do not respond to or cannot tolerate, other antihypertensive treatment.

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Moderate

Drug Interactions Atenolol and chlorthalidone may potentiate the action of other antihypertensive agents used concomitantly.

Drug interactionsby drug classView label on DailyMed
Moderate

Calcium channel blockers may also have an additive effect when given with atenolol and chlorthalidone.

Drug interactionsby drug classView label on DailyMed
Minor

Concomitant Use of Calcium Channel Blockers Bradycardia and heart block can occur and the left ventricular end diastolic pressure can rise when beta- blockers are administered with verapamil or diltiazem.

Warningsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.