Amlodipine and benazepril and Dalfampridine interaction

Amlodipine and benazepril and Dalfampridine: the Amlodipine and benazepril prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Amlodipine and benazepril (Amlodipine and Benazepril Hydrochloride) label · effective 2026-01-29

Moderate

Risk factors for the development of hyperkalemia include renal insufficiency, diabetes mellitus, and the concomitant use of potassium-sparing diuretics, potassium supplements, and/or potassium-containing salt substitutes.

Warnings and precautionsby drug classView label on DailyMed
Moderate

Potassium supplements/potassium-sparing diuretics: hyperkalemia ( 7.1 )

Drug interactionsby drug classView label on DailyMed
Moderate

Potassium-sparing diuretics (spironolactone, amiloride, triamterene, and others) or potassium supplements can increase the risk of hyperkalemia.

Drug interactionsby drug classView label on DailyMed
Minor

Benazepril Potassium Supplements and Potassium-Sparing Diuretics: Benazepril can attenuate potassium loss caused by thiazide diuretics.

Drug interactionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.