Amlodipine and Carbidopa, levodopa, and entacapone interaction

Amlodipine and Carbidopa, levodopa, and entacapone: the Carbidopa, levodopa, and entacapone prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Carbidopa, levodopa, and entacapone (Carbidopa, Levodopa and Entacapone) label · effective 2026-04-08

Moderate

Antihypertensive Agents Symptomatic postural hypotension has occurred when carbidopa/levodopa was added to the treatment of patients receiving antihypertensive drugs.

Drug interactionsby drug classView label on DailyMed
Moderate

When starting therapy with Carbidopa, levodopa and entacapone tablets, dosage adjustment of antihypertensive drug may be required.

Drug interactionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.