Amoxapine and Sevoflurane interaction

Amoxapine and Sevoflurane: both prescribing labels describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.

Moderate

Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.

What the FDA labels say

From the Sevoflurane (Ultane) label · effective 2025-01-13

Moderate

Consider having an anticholinergic and epinephrine available when administering sevoflurane for induction in this patient population.

Warningsby drug classView label on DailyMed
Minor

In most cases, bradycardia improved with decreasing the concentration of sevoflurane, manipulating the airway, or administering an anticholinergic or epinephrine.

Warningsby drug classView label on DailyMed

From the Amoxapine label · effective 2024-10-16

Moderate

Amoxapine may enhance the response to alcohol and the effects of barbiturates and other CNS depressants.

Drug interactionsby drug classView label on DailyMed

Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.

Open in the checker

Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.