Amphetamine and dextroamphetamine and Budesonide and formoterol interaction

Amphetamine and dextroamphetamine and Budesonide and formoterol: both prescribing labels flag this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

From the Budesonide and formoterol (Budesonide and Formoterol Fumarate Dihydrate) label · effective 2026-04-24

Major

Clinically significant cardiovascular effects and fatalities have been reported in association with excessive use of inhaled sympathomimetic drugs.

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Major

Fatalities have been reported in association with excessive use of inhaled sympathomimetic drugs.

Warnings and precautionsby drug classView label on DailyMed
Moderate

Therefore, budesonide and formoterol fumarate dihydrate, like all products containing sympathomimetic amines, should be used with caution in patients with cardiovascular disorders, especially coronary insufficiency, cardiac arrhythmias, and hypertension.

Warnings and precautionsby drug classView label on DailyMed
Moderate

Coexisting Conditions Budesonide and formoterol fumarate dihydrate, like all medications containing sympathomimetic amines, should be used with caution in patients with convulsive disorders or thyrotoxicosis and in those who are unusually responsive to sympathomimetic amines.

Warnings and precautionsby drug classView label on DailyMed

From the Amphetamine and dextroamphetamine (Adderall XR) label · effective 2026-04-30

Moderate

Tricyclic Antidepressants Clinical Impact May enhance the activity of tricyclic or sympathomimetic agents causing striking and sustained increases in the concentration of d-amphetamine in the brain; cardiovascular effects can be potentiated.

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Minor

Interference with Laboratory Tests Amphetamines can cause a significant elevation in plasma corticosteroid levels.

Drug interactionsby drug classView label on DailyMed
Minor

Amphetamines may interfere with urinary steroid determinations.

Drug interactionsby drug classView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.