Ampicillin and sulbactam and Gentamicin interaction

Ampicillin and sulbactam and Gentamicin: the Ampicillin and sulbactam prescribing label mentions this combination without an instruction to avoid it or change the dose.

Minor

Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.

What the FDA labels say

From the Ampicillin and sulbactam (UNASYN) label · effective 2026-07-09

Minor

UNASYN and aminoglycosides should not be reconstituted together due to the in vitro inactivation of aminoglycosides by the ampicillin component of UNASYN.

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.