Antacids (Tums, Maalox, Mylanta) and Diazepam interaction
Antacids (Tums, Maalox, Mylanta) and Diazepam: the Diazepam prescribing label mention this combination without an instruction to avoid it or change the dose.
Mentioned, no instruction to avoid. Worth knowing; rarely a reason to change anything on its own.
What the FDA labels say
From the Diazepam (Valium) label · effective 2026-08-11
Antacids Diazepam peak concentrations are 30% lower when antacids are administered concurrently.
The lower peak concentrations appear due to a slower rate of absorption, with the time required to achieve peak concentrations on average 20 - 25 minutes greater in the presence of antacids.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.