Aspirin and Dichlorphenamide interaction

Aspirin and Dichlorphenamide: the Dichlorphenamide prescribing label flags this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

From the Dichlorphenamide (Keveyis) label · effective 2026-03-04

Major

…contraindicated in the following circumstances: Hypersensitivity to dichlorphenamide or other sulfonamides [see Warnings and Precautions (5.1) ] Concomitant use of KEVEYIS and high dose aspirin [see Warnings and Precautions (5.2) and Drug Interactions (7.1) ] Severe pulmonary disease, limiting compensation to metabolic acidosis caused by KEVEYIS [see Warnings and Precautions…

Contraindicationsnames AspirinView label on DailyMed
Major

Concomitant use with high dose aspirin ( 4 )

Contraindicationsnames AspirinView label on DailyMed
Major

Therefore, the concomitant use of KEVEYIS and high-dose aspirin is contraindicated.

Warnings and precautionsnames AspirinView label on DailyMed
Major

The concomitant use of KEVEYIS and high-dose aspirin is contraindicated.

Drug interactionsnames AspirinView label on DailyMed
Major

Therefore, concomitant use of KEVEYIS and high-dose aspirin is contraindicated.

Drug interactionsnames AspirinView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.