Aspirin and dipyridamole and Ketorolac interaction

Aspirin and dipyridamole and Ketorolac: the Ketorolac prescribing label flag this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

From the Ketorolac (Ketorolac Tromethamine) label · effective 2024-12-31

Major

CONCOMITANT USE WITH NSAIDs Ketorolac tromethamine is CONTRAINDICATED in patients currently receiving aspirin or NSAIDs because of the cumulative risk of inducing serious NSAID-related side effects.

Boxed warningnames Aspirin and dipyridamoleView label on DailyMed
Major

Ketorolac tromethamine should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.

Contraindicationsnames Aspirin and dipyridamoleView label on DailyMed
Major

Ketorolac tromethamine is contraindicated in patients currently receiving aspirin or NSAIDs because of the cumulative risks of inducing serious NSAID-related adverse events.

Contraindicationsnames Aspirin and dipyridamoleView label on DailyMed
Major

This symptom complex typically occurs in asthmatic patients who experience rhinitis with or without nasal polyps, or who exhibit severe, potentially fatal bronchospasm after taking aspirin or other NSAIDs (see CONTRAINDICATIONS and PRECAUTIONS, PREEXISTING ASTHMA).

Warnings and precautionsnames Aspirin and dipyridamoleView label on DailyMed
Major

The use of aspirin in patients with aspirin- sensitive asthma has been associated with severe bronchospasm which can be fatal.

Warnings and precautionsnames Aspirin and dipyridamoleView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.