Aspirin and dipyridamole and Naproxen and esomeprazole interaction

Aspirin and dipyridamole and Naproxen and esomeprazole: the Naproxen and esomeprazole prescribing label flags this combination with the strongest language, such as a contraindication, a boxed warning, or an instruction to avoid it.

Major

Do not combine without a prescriber's guidance. The label language below is the strongest FDA uses.

What the FDA labels say

From the Naproxen and esomeprazole (Naproxen and esomeprazole magnesium) label · effective 2026-05-27

Major

• History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.

Contraindicationsnames Aspirin and dipyridamoleView label on DailyMed
Major

History of asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs.

Contraindicationsnames Aspirin and dipyridamoleView label on DailyMed
Major

Exacerbation of Asthma Related to Aspirin Sensitivity : Naproxen and esomeprazole magnesium delayed-release tablets are contraindicated in patients with aspirin-sensitive asthma.

Warnings and precautionsnames Aspirin and dipyridamoleView label on DailyMed
Major

Concomitant NSAID Use : Do not use naproxen and esomeprazole magnesium delayed-release tablets with other naproxen-containing products or other non-aspirin NSAIDs.

Warnings and precautionsnames Aspirin and dipyridamoleView label on DailyMed
Major

Exacerbation of Asthma Related to Aspirin Sensitivity A subpopulation of patients with asthma may have aspirin-sensitive asthma which may include chronic rhinosinusitis complicated by nasal polyps; severe, potentially fatal bronchospasm; and/or intolerance to aspirin and other NSAIDs.

Warnings and precautionsnames Aspirin and dipyridamoleView label on DailyMed

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Not medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.