Aspirin and Venlafaxine interaction
Aspirin and Venlafaxine: the Venlafaxine prescribing label describe an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Venlafaxine (Venlafaxine Hydrochloride) label · effective 2025-01-31
Patients should be cautioned about the increased risk of bleeding associated with the concomitant use of Venlafaxine Extended Release Tablets and NSAIDs, aspirin, or other drugs that affect coagulation.
These studies have also shown that concurrent use of an NSAID or aspirin may potentiate this risk of bleeding.
Concomitant use of aspirin, Nonsteroidal Anti-Inflammatory Drugs (NSAIDs), warfarin, and other anticoagulants may add to this risk.
Drugs that Interfere with Hemostasis (e.g., NSAID’s, Aspirin, and Warfarin) Serotonin release by platelets plays an important role in hemostasis.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.